5ONH

Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

Summary for 5ONH

Entry DOI	10.2210/pdb5onh/pdb
Related	4AQ7 5OMW 5ON2 5ON3
Descriptor	Leucine--tRNA ligase, L-leucyl-tRNA(Leu), ZINC ION, ... (6 entities in total)
Functional Keywords	reaction catalysed: atp + l-leucine + trna(leu) = amp + diphosphate + l-leucyl-trna(leu) protein translation, aminoacyl-trna activity, leucine-trna ligase, class ia, translation, ligase
Biological source	Escherichia coli K-12 More
Total number of polymer chains	4
Total formula weight	256966.49
Authors	Palencia, A.,Cusack, S. (deposition date: 2017-08-03, release date: 2017-11-15, Last modification date: 2024-01-17)
Primary citation	Dulic, M.,Cvetesic, N.,Zivkovic, I.,Palencia, A.,Cusack, S.,Bertosa, B.,Gruic-Sovulj, I. Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430:1-16, 2018 Cited by PubMed: 29111343 DOI: 10.1016/j.jmb.2017.10.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation