PDB: 153 件ウェブページステータス検索Chemie searchBIRD

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4JLQ	Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2 分子名称: Nuclear polyadenylated RNA-binding protein NAB2, Transportin-1 著者 Sampathkumar, P, Gizzi, A, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) 登録日 2013-03-12 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Crystal structure of human Karyopherin beta 2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2. J.Struct.Funct.Genom., 14, 2013
4OO6	Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) 分子名称: RNA-binding protein 39, Transportin-1 著者 Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) 登録日 2014-01-30 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) to be published
7UNK	Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex 分子名称: Histone H3, Histone H4, Histone chaperone, ... 著者 Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y. 登録日 2022-04-11 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex. Proc.Natl.Acad.Sci.USA, 119, 2022
5OWU	Kap95:Nup1 complex 分子名称: Importin subunit beta-1, Nucleoporin NUP1 著者 Stewart, M. 登録日 2017-09-04 公開日 2017-10-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p. J. Mol. Biol., 349, 2005
1IBR	COMPLEX OF RAN WITH IMPORTIN BETA 分子名称: GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ... 著者 Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A. 登録日 1999-05-14 公開日 1999-06-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural view of the Ran-Importin beta interaction at 2.3 A resolution Cell(Cambridge,Mass.), 97, 1999
7VPW	Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724) 分子名称: BRCA1-associated protein 1 (BAP1), Transportin-1 著者 Yang, T.J, Hsu, S.T.D. 登録日 2021-10-18 公開日 2022-04-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.76 Å) 主引用文献 Tumor suppressor BAP1 nuclear import is governed by transportin-1. J.Cell Biol., 221, 2022
3EA5	Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ... 著者 Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B. 登録日 2008-08-24 公開日 2008-10-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383, 2008
8HQ4	B27 in complex with CRM1-Ran-RanBP1 分子名称: 3-[(4-fluorophenyl)carbonylamino]-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ... 著者 Lei, Y, Sun, Q. 登録日 2022-12-13 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 B27 in complex with CRM1-Ran-RanBP1 To Be Published
8HQ5	G6 in complex with CRM1-Ran-RanBP1 分子名称: 3-[(4-bromophenyl)carbonylamino]-4-[4-(5-chloranyl-2-methyl-phenyl)piperazin-1-yl]benzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2022-12-13 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 F1 in complex with CRM1-Ran-RanBP1 To Be Published
1F59	IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX 分子名称: FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1 著者 Bayliss, R, Littlewood, T, Stewart, M. 登録日 2000-06-13 公開日 2000-08-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell(Cambridge,Mass.), 102, 2000
1O6P	Importin Beta bound to a GLFG Nucleoporin peptide 分子名称: IMPORTIN BETA-1 SUBUNIT, SYNTHETIC GLFG PEPTIDE 著者 Bayliss, R, Stewart, M. 登録日 2002-10-10 公開日 2003-04-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta J.Biol.Chem., 277, 2002
1O6O	Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form 分子名称: IMPORTIN BETA-1 SUBUNIT, NUCLEOPORIN NSP1 著者 Bayliss, R, Stewart, M. 登録日 2002-10-10 公開日 2003-10-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta J.Biol.Chem., 277, 2002
1WA5	Structure of the Cse1:Imp-alpha:RanGTP complex 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ... 著者 Stewart, M. 登録日 2004-10-23 公開日 2004-12-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the assembly of a nuclear export complex. Nature, 432, 2004
3GJX	Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R. 登録日 2009-03-09 公開日 2009-05-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP. Science, 2009
1Z3H	The exportin Cse1 in its cargo-free, cytoplasmic state 分子名称: Importin alpha re-exporter, MAGNESIUM ION 著者 Cook, A, Fernandez, E, Lindner, D, Ebert, J, Schlenstedt, G, Conti, E. 登録日 2005-03-12 公開日 2005-05-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The structure of the nuclear export receptor cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding Mol.Cell, 18, 2005
2OT8	Karyopherin Beta2/Transportin-hnRNPM NLS Complex 分子名称: Heterogeneous nuclear ribonucleoprotein M, Transportin-1 著者 Cansizoglu, A.E, Chook, Y.M. 登録日 2007-02-07 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure-based design of a pathway-specific nuclear import inhibitor. Nat.Struct.Mol.Biol., 14, 2007
2P8Q	Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain 分子名称: Importin beta-1 subunit, Snurportin-1 著者 Mitrousis, G, Cingolani, G. 登録日 2007-03-22 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
2Q5D	Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form 分子名称: Importin beta-1 subunit, Snurportin-1 著者 Mitrousis, G, Cingolani, G. 登録日 2007-05-31 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
1QGR	STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH) 分子名称: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) 著者 Cingolani, G, Petosa, C, Weis, K, Muller, C.W. 登録日 1999-05-04 公開日 1999-05-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of importin-beta bound to the IBB domain of importin-alpha. Nature, 399, 1999
7B51	Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528 分子名称: BETA-MERCAPTOETHANOL, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Shaikhqasem, A, Ficner, R. 登録日 2020-12-03 公開日 2021-03-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP. Acta Crystallogr.,Sect.F, 77, 2021
1QGK	STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA 分子名称: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) 著者 Cingolani, G, Petosa, C, Weis, K, Muller, C.W. 登録日 1999-04-29 公開日 1999-05-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of importin-beta bound to the IBB domain of importin-alpha. Nature, 399, 1999
2QMR	Karyopherin beta2/transportin 分子名称: Transportin-1 著者 Cansizoglu, A.E, Chook, Y.M. 登録日 2007-07-16 公開日 2007-10-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational heterogeneity of karyopherin beta2 is segmental Structure, 15, 2007
7CND	NCI-1 in complex with CRM1-Ran-RanBP1 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, CRM1 isoform 1, ... 著者 Sun, Q, Lei, Y. 登録日 2020-07-31 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1. J.Med.Chem., 64, 2021
7CYL	Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Chook, Y.M. 登録日 2020-09-03 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep, 11, 2021
1QBK	STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX 分子名称: KARYOPHERIN BETA2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Chook, Y.M, Blobel, G. 登録日 1999-04-23 公開日 1999-06-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Nature, 399, 1999

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