2Y79
| STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS | 分子名称: | CALCIUM ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Cho, H.Y, Cho, H.J, Kang, B.S. | 登録日 | 2011-01-30 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen. FEBS Lett., 585, 2011
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2Y8H
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3BJC
| Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor | 分子名称: | 5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide, MAGNESIUM ION, ZINC ION, ... | 著者 | Chen, G, Wang, H, Howard, R, Cai, J, Wan, Y, Ke, H. | 登録日 | 2007-12-03 | 公開日 | 2008-04-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies BIOCHEM.PHARM., 75, 2008
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3C2W
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3CI6
| Crystal structure of the GAF domain from Acinetobacter phosphoenolpyruvate-protein phosphotransferase | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Cuff, M.E, Shackelford, G, Kim, Y, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-03-10 | 公開日 | 2008-05-13 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of the GAF domain from Acinetobacter phosphoenolpyruvate-protein phosphotransferase. TO BE PUBLISHED
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3DBA
| Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C | 分子名称: | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GLYCEROL, GUANOSINE-3',5'-MONOPHOSPHATE | 著者 | Martinez, S.E, Heikaus, C.C, Klevit, R.E, Beavo, J.A. | 登録日 | 2008-05-30 | 公開日 | 2008-07-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change. J.Biol.Chem., 283, 2008
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3G6O
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3IBJ
| X-ray structure of PDE2A | 分子名称: | MAGNESIUM ION, ZINC ION, cGMP-dependent 3',5'-cyclic phosphodiesterase | 著者 | Pandit, J. | 登録日 | 2009-07-16 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct. Proc.Natl.Acad.Sci.USA, 106, 2009
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3IBR
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3JAB
| Domain organization and conformational plasticity of the G protein effector, PDE6 | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, ... | 著者 | Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A. | 登録日 | 2015-05-26 | 公開日 | 2015-06-10 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6. J.Biol.Chem., 290, 2015
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3JBQ
| Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6 | 分子名称: | GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, IgG1-kappa 2E8 heavy chain, ... | 著者 | Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A. | 登録日 | 2015-09-17 | 公開日 | 2015-09-30 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6. J.Biol.Chem., 290, 2015
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3K2N
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3KO6
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3LFV
| crystal structure of unliganded PDE5A GAF domain | 分子名称: | cGMP-specific 3',5'-cyclic phosphodiesterase | 著者 | Wang, H, Robinson, H, Ke, H. | 登録日 | 2010-01-18 | 公開日 | 2010-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain. J.Biol.Chem., 285, 2010
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3MF0
| Crystal structure of PDE5A GAF domain (89-518) | 分子名称: | cGMP-specific 3',5'-cyclic phosphodiesterase | 著者 | Wang, H, Robinson, H, Ke, H. | 登録日 | 2010-04-01 | 公開日 | 2010-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain. J.Biol.Chem., 285, 2010
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3NHQ
| The dark Pfr structure of the photosensory core module of P. aeruginosa Bacteriophytochrome | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | 著者 | Yang, X, Ren, Z, Kuk, J, Moffat, K. | 登録日 | 2010-06-14 | 公開日 | 2011-11-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Temperature-scan cryocrystallography reveals reaction intermediates in bacteriophytochrome. Nature, 479, 2011
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3NOP
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3NOT
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3NOU
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3O5Y
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3OOV
| Crystal structure of a methyl-accepting chemotaxis protein, residues 122 to 287 | 分子名称: | GLYCEROL, Methyl-accepting chemotaxis protein, putative | 著者 | Joachimiak, A, Duke, N.E.C, Hatzos-Skintges, C, Mulligan, R, Clancy, S, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-08-31 | 公開日 | 2010-09-08 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a methyl-accepting chemotaxis protein, residues 122 to 287 To be Published
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3P01
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3S7N
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3S7O
| Crystal Structure of the Infrared Fluorescent D207H variant of Deinococcus Bacteriophytochrome chromophore binding domain at 1.24 angstrom resolution | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome, GLYCEROL | 著者 | Forest, K.T, Auldridge, M.E, Satyshur, K.A, Anstrom, D.M. | 登録日 | 2011-05-26 | 公開日 | 2011-12-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Structure-guided engineering enhances a phytochrome-based infrared fluorescent protein. J.Biol.Chem., 287, 2012
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3S7P
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