3MF0

Crystal structure of PDE5A GAF domain (89-518)

Summary for 3MF0

Entry DOI	10.2210/pdb3mf0/pdb
Related	3LFV
Descriptor	cGMP-specific 3',5'-cyclic phosphodiesterase (1 entity in total)
Functional Keywords	gaf, cgmp signal, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	97622.50
Authors	Wang, H.,Robinson, H.,Ke, H. (deposition date: 2010-04-01, release date: 2010-09-22, Last modification date: 2024-02-21)
Primary citation	Wang, H.,Robinson, H.,Ke, H. Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain. J.Biol.Chem., 285:38149-38156, 2010 Cited by PubMed: 20861010 DOI: 10.1074/jbc.M110.141614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation