3MF0

Crystal structure of PDE5A GAF domain (89-518)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	cGMP-specific 3',5'-cyclic phosphodiesterase	polymer	432	48811.3	2	UniProt (O76074) Pfam (PF01590)	Homo sapiens (human)	cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE

Sequence modifications

A, B: 89 - 518 (UniProt: O76074)

PDB	External Database	Details
Ser 149	Cys 149	engineered mutation
Arg 519	-	expression tag
Asn 520	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97622.5
All*	Total formula weight	97622.5

*Water molecules are not included.