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4YSI
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BU of 4ysi by Molmil
Structure of USP7 with a novel viral protein
分子名称: GLYCEROL, SER-PRO-GLY-GLU-GLY-PRO-SER-GLY, Ubiquitin carboxyl-terminal hydrolase 7
著者Chavoshi, S, Saridakis, V.
登録日2015-03-17
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Structure of USP7 with a novel viral protein
J.Biol.Chem., 2016
6F8F
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BU of 6f8f by Molmil
Co-crystal structure of SPOP MATH domain and human Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
6F8G
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BU of 6f8g by Molmil
Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
6I41
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BU of 6i41 by Molmil
Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-08
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I5P
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BU of 6i5p by Molmil
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-14
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I68
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BU of 6i68 by Molmil
Co-crystal structure of human SPOP MATH domain (M117V) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-15
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I7A
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BU of 6i7a by Molmil
Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-16
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
7D3D
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BU of 7d3d by Molmil
Crystal structure of SPOP bound with a peptide
分子名称: GLU-VAL-SER-ILE-ILE-GLN-GLY-ALA-ASP-SER-THR-THR, GLYCEROL, Speckle-type POZ protein
著者Yang, C.-G, Gan, J.H.
登録日2020-09-18
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A peptide binder of E3 ligase adaptor SPOP disrupts oncogenic SPOP-protein interactions in kidney cancer cells.
Chin.J.Chem., 39, 2021
7KLZ
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BU of 7klz by Molmil
Structure of SPOP MATH domain in complex with a Geminin peptide
分子名称: Geminin peptide, PHOSPHATE ION, Speckle-type POZ protein
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2020-11-01
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.
Nat Commun, 12, 2021
7KPI
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BU of 7kpi by Molmil
Crystal structure of the SPOP MATH domain
分子名称: Speckle-type POZ protein
著者Usher, E.T, Boal, A.K.
登録日2020-11-11
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity.
J.Biol.Chem., 296, 2021
7KPK
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BU of 7kpk by Molmil
Crystal structure of the SPOP MATH domain in complex with a fragment of Pdx1
分子名称: Pdx1 peptide, Speckle-type POZ protein
著者Usher, E.T, Boal, A.K.
登録日2020-11-11
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity.
J.Biol.Chem., 296, 2021
7LIN
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BU of 7lin by Molmil
X-ray structure of SPOP MATH domain (D140G) in complex with a 53BP1 peptide
分子名称: SULFATE ION, Speckle-type POZ protein, TP53-binding protein 1 peptide
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIO
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BU of 7lio by Molmil
X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide
分子名称: Speckle-type POZ protein, TP53-binding protein 1 peptide
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIP
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BU of 7lip by Molmil
X-ray structure of SPOP MATH domain (D140G)
分子名称: SULFATE ION, Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIQ
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BU of 7liq by Molmil
X-ray structure of SPOP MATH domain (S119A)
分子名称: Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
8DWS
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BU of 8dws by Molmil
Full-length E47K SPOP
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
登録日2022-08-02
公開日2023-01-18
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWT
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BU of 8dwt by Molmil
SPOP W22R Form 2
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
登録日2022-08-02
公開日2023-01-18
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWU
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BU of 8dwu by Molmil
SPOP W22R Form 1
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B.
登録日2022-08-02
公開日2023-01-18
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWV
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BU of 8dwv by Molmil
Full-length wild type SPOP
分子名称: Speckle-type POZ protein
著者Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
登録日2022-08-02
公開日2023-01-18
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
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