7LIO

X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide

Summary for 7LIO

Entry DOI	10.2210/pdb7lio/pdb
Descriptor	Speckle-type POZ protein, TP53-binding protein 1 peptide (2 entities in total)
Functional Keywords	spop, 53bp1, dna damage response, homologous recombination, ubiquitin ligase, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	35826.84
Authors	Botuyan, M.V.,Cui, G.,Mer, G. (deposition date: 2021-01-27, release date: 2021-04-14, Last modification date: 2023-10-18)
Primary citation	Wang, D.,Ma, J.,Botuyan, M.V.,Cui, G.,Yan, Y.,Ding, D.,Zhou, Y.,Krueger, E.W.,Pei, J.,Wu, X.,Wang, L.,Pei, H.,McNiven, M.A.,Ye, D.,Mer, G.,Huang, H. ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Sci Adv, 7:-, 2021 Cited by PubMed: 34144977 DOI: 10.1126/sciadv.abd9208 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.01 Å)

Structure validation