8DWS

Full-length E47K SPOP

Summary for 8DWS

• Entry DOI: 10.2210/pdb8dws/pdb
• EMDB information: 27758
• Descriptor: Speckle-type POZ protein (1 entity in total)
• Functional Keywords: spop, ubiquitination, cullin, oncoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 7
• Total formula weight: 295283.95

Authors

Cuneo, M.J.,Mittag, T.,O'Flynn, B.,Lo, Y.H. (deposition date: 2022-08-02, release date: 2023-01-18, Last modification date: 2023-03-22)

• Primary citation: Cuneo, M.J.,O'Flynn, B.G.,Lo, Y.H.,Sabri, N.,Mittag, T.; Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.; Mol.Cell, 83:731-745.e4, 2023; PubMed: 36693379; DOI: 10.1016/j.molcel.2022.12.033

Experimental method

ELECTRON MICROSCOPY (3.73 Å)