6I5P
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
Summary for 6I5P
Entry DOI | 10.2210/pdb6i5p/pdb |
Related | 6I41 |
Descriptor | Speckle-type POZ protein, Bromodomain-containing protein 3 (3 entities in total) |
Functional Keywords | ligase nuclear cancer ubiquitination, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 70208.79 |
Authors | Ostertag, M.S.,Popowicz, G.M.,Sattler, M. (deposition date: 2018-11-14, release date: 2019-05-08, Last modification date: 2024-01-24) |
Primary citation | Ostertag, M.S.,Hutwelker, W.,Plettenburg, O.,Sattler, M.,Popowicz, G.M. Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants. J.Mol.Biol., 431:2213-2221, 2019 Cited by PubMed: 31026449DOI: 10.1016/j.jmb.2019.04.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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