6I5P
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Speckle-type POZ protein | polymer | 145 | 16616.2 | 4 | UniProt (O43791) Pfam (PF22486) | Homo sapiens (Human) | HIB homolog 1,Roadkill homolog 1 |
| 2 | B, D, F, H (B, D, F, H) | Bromodomain-containing protein 3 | polymer | 9 | 936.0 | 4 | UniProt (Q15059) | Homo sapiens (Human) | RING3-like protein |
| 3 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 486 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 28 - 166 (UniProt: O43791)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Met 24 | - | expression tag |
| Ala 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Lys 47 | Glu 47 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 70208.8 | |
| All* | Total formula weight | 70208.8 |
