2QJS
 
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2FU9
 | | Zinc-beta-lactamase L1 from stenotrophomonas maltophilia (mp2 inhibitor complex) | | 分子名称: | GLYCEROL, Metallo-beta-lactamase L1, N-[(BENZYLOXY)CARBONYL]-L-CYSTEINYLGLYCINE, ... | | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | | 登録日 | 2006-01-26 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008
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4UWS
 | | VIM-26-PEG. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding. | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, METALLO-BETA-LACTAMASE VIM-26, ... | | 著者 | Leiros, H.-K.S, Edvardsen, K.S.W, Bjerga, G.E.K, Samuelsen, O. | | 登録日 | 2014-08-14 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases.
FEBS J., 282, 2015
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4WD6
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4UWP
 | | Penta Zn1 coordination. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding. | | 分子名称: | METALLO-BETA-LACTAMASE VIM-26, ZINC ION | | 著者 | Leiros, H.-K.S, Edvardsen, K.S.W, Bjerga, G.E.K, Samuelsen, O. | | 登録日 | 2014-08-14 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases.
FEBS J., 282, 2015
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2FU7
 | | Zinc-beta-lactamase L1 from stenotrophomonas maltophilia (Cu-substituted form) | | 分子名称: | 1,10-PHENANTHROLINE, COPPER (II) ION, GLYCEROL, ... | | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | | 登録日 | 2006-01-26 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008
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2FU8
 | | Zinc-beta-lactamase L1 from stenotrophomonas maltophilia (d-captopril complex) | | 分子名称: | 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, GLYCEROL, Metallo-beta-lactamase L1, ... | | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | | 登録日 | 2006-01-26 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008
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2QDT
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4UWO
 | | Native di-zinc VIM-26. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding. | | 分子名称: | GLYCEROL, METALLO-BETA-LACTAMASE VIM-26, SODIUM ION, ... | | 著者 | Leiros, H.-K.S, Edvardsen, K.S.W, Bjerga, G.E.K, Samuelsen, O. | | 登録日 | 2014-08-14 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.555 Å) | | 主引用文献 | Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases.
FEBS J., 282, 2015
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2QIN
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2FU6
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2R2D
 | | Structure of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens | | 分子名称: | GLYCEROL, PHOSPHATE ION, ZINC ION, ... | | 著者 | Liu, D, Thomas, P.W, Momb, J, Hoang, Q, Petsko, G.A, Ringe, D, Fast, W. | | 登録日 | 2007-08-24 | | 公開日 | 2007-10-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens.
Biochemistry, 46, 2007
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2VW8
 | | Crystal Structure of Quinolone signal response protein pqsE from Pseudomonas aeruginosa | | 分子名称: | 1,2-ETHANEDIOL, CACODYLATE ION, FE (II) ION, ... | | 著者 | Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Oke, M, Naismith, J.H, White, M.F. | | 登録日 | 2008-06-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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7L52
 | | Crystal Structure of the Metallo Beta Lactamase L1 from Stenotrophomonas maltophilia Determined by Serial Crystallography | | 分子名称: | Putative metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase), ZINC ION | | 著者 | Wilamowski, M, Kim, Y, Sherrell, D.A, Lavens, A, Maltseva, N, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-12-21 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of the Metallo Beta Lactamase L1 from Stenotrophomonas maltophilia Determined by Serial Crystallography
To Be Published
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2WHG
 | | Crystal Structure of the Di-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | | 分子名称: | CITRATE ANION, VIM-4 METALLO-BETA-LACTAMASE, ZINC ION | | 著者 | Lassaux, P, Traore, D.A.K, Galleni, M, Ferrer, J.L. | | 登録日 | 2009-05-05 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Biochemical and Structural Characterization of the Subclass B1 Metallo-{Beta}-Lactamase Vim-4.
Antimicrob.Agents Chemother., 55, 2011
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7KGX
 | | Structure of PQS Response Protein PqsE in Complex with 4-(3-(2-methyl-2-morpholinobutyl)ureido)-N-(thiazol-2-yl)benzamide | | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-({[(2R)-2-methyl-2-(morpholin-4-yl)butyl]carbamoyl}amino)-N-(1,3-thiazol-2-yl)benzamide, FE (III) ION | | 著者 | Jeffrey, P.D, Taylor, I.R, Bassler, B.L. | | 登録日 | 2020-10-19 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.
Acs Chem.Biol., 16, 2021
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7KGW
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2WRS
 | | Crystal Structure of the Mono-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | | 分子名称: | BETA-LACTAMASE VIM-4, CITRATE ANION, CITRIC ACID, ... | | 著者 | Lassaux, P, Hamel, M, Gulea, M, Delbruck, H, Traore, D.A.K, Mercuri, P.S, Horsfall, L, Dehareng, D, Gaumont, A.-C, Frere, J.-M, Ferrer, J.-L, Hoffmann, K, Galleni, M, Bebrone, C. | | 登録日 | 2009-09-02 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-Beta-Lactamases.
J.Med.Chem., 53, 2010
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2UYX
 | | metallo-beta-lactamase (1BC2) single point mutant D120S | | 分子名称: | BETA-LACTAMASE II, GLYCEROL, ZINC ION | | 著者 | Larrull, L.I, Fabiane, S.M, Kowalski, J.M, Bennett, B, Sutton, B.J, Vila, A.J. | | 登録日 | 2007-04-20 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity.
J. Biol. Chem., 282, 2007
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7L5F
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4EXY
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4EXS
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8D2Z
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4F6H
 | | Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-b-lactamase active site | | 分子名称: | Beta-lactamase, PHOSPHATE ION, SULFATE ION, ... | | 著者 | Horton, L.B, Shanker, S, Sankaran, B, Mikulski, R, Brown, N.G, Phillips, K, Lykissa, E, Prasad, B.V.V, Palzkill, T.G. | | 登録日 | 2012-05-14 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.744 Å) | | 主引用文献 | Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-beta-lactamase active site
Antimicrob.Agents Chemother., 56, 2012
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4EYL
 | | Crystal structure of NDM-1 bound to hydrolyzed meropenem | | 分子名称: | (2S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-2H-pyrro le-5-carboxylic acid, Beta-lactamase NDM-1, ZINC ION | | 著者 | Strynadka, N.C.J, King, D.T. | | 登録日 | 2012-05-01 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | New Delhi Metallo-Beta-Lactamase: Structural Insights into Beta-Lactam Recognition and Inhibition
J.Am.Chem.Soc., 134, 2012
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