6KXO

Crystal Structure Of VIM-2 Metallo-beta-lactamase In Complex With Inhibitor NO9

Summary for 6KXO

• Entry DOI: 10.2210/pdb6kxo/pdb
• Descriptor: Beta-lactamase class B VIM-2, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 52410.06

Authors

Wachino, J. (deposition date: 2019-09-12, release date: 2020-02-19, Last modification date: 2023-11-22)

• Primary citation: Wachino, J.I.,Jin, W.,Kimura, K.,Kurosaki, H.,Sato, A.,Arakawa, Y.; Sulfamoyl Heteroarylcarboxylic Acids as Promising Metallo-beta-Lactamase Inhibitors for Controlling Bacterial Carbapenem Resistance.; Mbio, 11:-, 2020; PubMed: 32184250; DOI: 10.1128/mBio.03144-19

Experimental method

X-RAY DIFFRACTION (1.49 Å)