4UWS

VIM-26-PEG. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding.

Summary for 4UWS

Entry DOI	10.2210/pdb4uws/pdb
Related	4UWO 4UWP 4UWR
Descriptor	METALLO-BETA-LACTAMASE VIM-26, SULFATE ION, ZINC ION, ... (6 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, drug binding site
Biological source	KLEBSIELLA PNEUMONIAE
Total number of polymer chains	1
Total formula weight	28469.45
Authors	Leiros, H.-K.S.,Edvardsen, K.S.W.,Bjerga, G.E.K.,Samuelsen, O. (deposition date: 2014-08-14, release date: 2015-02-04, Last modification date: 2024-01-10)
Primary citation	Leiros, H.S.,Edvardsen, K.S.W.,Bjerga, G.E.K.,Samuelsen, O. Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases. FEBS J., 282:1031-, 2015 Cited by PubMed: 25601024 DOI: 10.1111/FEBS.13200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation