2YZ3
Crystallographic Investigation of Inhibition Mode of the VIM-2 Metallo-beta-lactamase from Pseudomonas aeruginosa with Mercaptocarboxylate Inhibitor
Summary for 2YZ3
Entry DOI | 10.2210/pdb2yz3/pdb |
Descriptor | Metallo-beta-lactamase, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | metallo-beta-lactamase, enzyme-inhibitor complex, hydrolase |
Biological source | Pseudomonas putida |
Total number of polymer chains | 2 |
Total formula weight | 57800.20 |
Authors | Yamaguchi, Y.,Yamagata, Y.,Arakawa, Y.,Kurosaki, H. (deposition date: 2007-05-02, release date: 2008-03-11, Last modification date: 2024-03-13) |
Primary citation | Yamaguchi, Y.,Jin, W.,Matsunaga, K.,Ikemizu, S.,Yamagata, Y.,Wachino, J.,Shibata, N.,Arakawa, Y.,Kurosaki, H. Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor. J.Med.Chem., 50:6647-6653, 2007 Cited by PubMed: 18052313DOI: 10.1021/jm701031n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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