1HJ9
| Atomic resolution structures of trypsin provide insight into structural radiation damage | Descriptor: | ANILINE, BETA-TRYPSIN, CALCIUM ION, ... | Authors: | Leiros, H.-K.S, McSweeney, S.M, Smalas, A.O. | Deposit date: | 2001-01-10 | Release date: | 2002-01-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Atomic Resolution Structure of Trypsin Provide Insight Into Structural Radiation Damage Acta Crystallogr.,Sect.D, 57, 2001
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1HJ8
| 1.00 AA Trypsin from Atlantic Salmon | Descriptor: | BENZAMIDINE, CALCIUM ION, SULFATE ION, ... | Authors: | Leiros, H.-K.S, Mcsweeney, S.M, Smalas, A.O. | Deposit date: | 2001-01-09 | Release date: | 2002-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Atomic Resolution Structure of Trypsin Provide Insight Into Structural Radiation Damage Acta Crystallogr.,Sect.D, 57, 2001
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8PEA
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8PEC
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8PEB
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8BHX
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2JH3
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7OBN
| Structural investigations of a new L3 DNA ligase: structure-function analysis | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3'), DNA ligase, ... | Authors: | Leiros, H.-K.S, Williamson, A. | Deposit date: | 2021-04-23 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Bacteriophage origin of some minimal ATP-dependent DNA ligases: a new structure from Burkholderia pseudomallei with striking similarity to Chlorella virus ligase. Sci Rep, 11, 2021
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1UTM
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 2-PHENYLETHYLAMINE, CALCIUM ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-09 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTN
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BENZYLAMINE, CALCIUM ION, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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4AOV
| DpIDH-NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism | Descriptor: | ISOCITRATE DEHYDROGENASE [NADP], ISOCITRIC ACID, MAGNESIUM ION, ... | Authors: | Leiros, H.-K.S, Fedoy, A.-E, Leiros, I, Steen, I.H. | Deposit date: | 2012-03-30 | Release date: | 2012-07-11 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | The Complex Structures of Isocitrate Dehydrogenase from Clostridium Thermocellum and Desulfotalea Psychrophila Suggest a New Active Site Locking Mechanism FEBS Open Bio., 2, 2012
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4D1W
| A H224Y mutant for VIM-7 from Pseudomonas aeruginosa | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | Deposit date: | 2014-05-05 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58, 2014
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4D1V
| A F218Y mutant of VIM-7 from Pseudomonas aeruginosa | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | Deposit date: | 2014-05-05 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58, 2014
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4D1U
| A D120A mutant of VIM-7 from Pseudomonas aeruginosa | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | Deposit date: | 2014-05-05 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58, 2014
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4D1T
| High resolution structure of native tVIM-7 from Pseudomonas aeruginosa | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | Deposit date: | 2014-05-05 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58, 2014
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1UTO
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 2-PHENYLETHYLAMINE, CALCIUM ION, GLYCEROL, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTJ
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | BENZYLAMINE, CALCIUM ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTK
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | CALCIUM ION, SULFATE ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTP
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 4-PHENYLBUTYLAMINE, CALCIUM ION, GLYCEROL, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTL
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-PHENYLPROPYLAMINE, CALCIUM ION, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTQ
| Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | CALCIUM ION, GLYCEROL, TRYPSINOGEN | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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2V28
| Apo structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H | Descriptor: | PHENYLALANINE-4-HYDROXYLASE, SULFATE ION | Authors: | Leiros, H.-K.S, Pey, A.L, Innselset, M, Moe, E, Leiros, I, Steen, I.H, Martinez, A. | Deposit date: | 2007-06-04 | Release date: | 2007-06-19 | Last modified: | 2018-10-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability. J.Biol.Chem., 282, 2007
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2V27
| Structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H | Descriptor: | FE (III) ION, PHENYLALANINE HYDROXYLASE, SULFATE ION | Authors: | Leiros, H.-K.S, Pey, A.L, Innselset, M, Moe, E, Leiros, I, Steen, I.H, Martinez, A. | Deposit date: | 2007-06-03 | Release date: | 2007-06-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability. J.Biol.Chem., 282, 2007
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2VPA
| High resolution crystal structure of the antibiotic resistance protein NimA from Deinococcus radiodurans | Descriptor: | ACETATE ION, NIMA-RELATED PROTEIN, PYRUVIC ACID | Authors: | Leiros, H.-K.S, Tedesco, C, McSweeney, S.M. | Deposit date: | 2008-02-27 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-Resolution Structure of the Antibiotic Resistance Protein Nima from Deinococcus Radiodurans. Acta Crystallogr.,Sect.F, 64, 2008
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4UWO
| Native di-zinc VIM-26. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding. | Descriptor: | GLYCEROL, METALLO-BETA-LACTAMASE VIM-26, SODIUM ION, ... | Authors: | Leiros, H.-K.S, Edvardsen, K.S.W, Bjerga, G.E.K, Samuelsen, O. | Deposit date: | 2014-08-14 | Release date: | 2015-02-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.555 Å) | Cite: | Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases. FEBS J., 282, 2015
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