PDB: 109 件ウェブページステータス検索Chemie searchBIRD

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2W6M	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series 分子名称: (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W70	Crystal structure of Biotin carboxylase from E. coli in complex with the amino-thiazole-pyrimidine fragment 分子名称: 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6Q	Crystal structure of Biotin carboxylase from E. coli in complex with the triazine-2,4-diamine fragment 分子名称: 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W71	Crystal structure of Biotin carboxylase from E. coli in complex with the imidazole-pyrimidine inhibitor 分子名称: 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine 分子名称: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment 分子名称: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6N	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series 分子名称: 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
3HBL	Crystal Structure of S. aureus Pyruvate Carboxylase T908A Mutant 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-05-04 公開日 2009-06-30 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HB9	Crystal Structure of S. aureus Pyruvate Carboxylase A610T Mutant 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-05-04 公開日 2009-06-30 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HO8	Crystal Structure of S. aureus Pyruvate Carboxylase in complex with Coenzyme A 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-06-01 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3JZF	Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazoles series 分子名称: 2-[(2-chlorobenzyl)amino]-1-(cyclohexylmethyl)-1H-benzimidazole-5-carboxamide, Biotin carboxylase, CARBONATE ION 著者 Orth, P. 登録日 2009-09-23 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3JZI	Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series 分子名称: 7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide, Biotin carboxylase 著者 Cheng, C, Shipps, G.W, Yang, Z, Sun, B, Kawahata, N, Soucy, K, Soriano, A, Orth, P, Xiao, L, Mann, P, Black, T. 登録日 2009-09-23 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3JRW	Phosphorylated BC domain of ACC2 分子名称: Acetyl-CoA carboxylase 2 著者 Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. 登録日 2009-09-09 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK Biochem.Biophys.Res.Commun., 391, 2010
3JRX	Crystal structure of the BC domain of ACC2 in complex with soraphen A 分子名称: Acetyl-CoA carboxylase 2, SORAPHEN A 著者 Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. 登録日 2009-09-09 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK. Biochem.Biophys.Res.Commun., 391, 2010
3N6R	CRYSTAL STRUCTURE OF the holoenzyme of PROPIONYL-COA CARBOXYLASE (PCC) 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase, alpha subunit, ... 著者 Huang, C.S, Sadre-Bazzaz, K, Tong, L. 登録日 2010-05-26 公開日 2010-08-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. Nature, 466, 2010
3OUZ	Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, D-MALATE, ... 著者 Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-09-15 公開日 2010-10-13 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni TO BE PUBLISHED
3OUU	Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex from Campylobacter jejuni 分子名称: Biotin carboxylase, CACODYLATE ION, CALCIUM ION, ... 著者 Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-09-15 公開日 2010-10-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.252 Å) 主引用文献 Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex from Campylobacter jejuni TO BE PUBLISHED
3RUP	Crystal structure of E.coli biotin carboxylase in complex with two ADP and two Ca ions 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, CALCIUM ION, ... 著者 Chou, C.Y, Tong, L. 登録日 2011-05-05 公開日 2011-05-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
3RV4	Crystal structure of E.coli biotin carboxylase R16E mutant in complex with Mg-ADP and bicarbonate 分子名称: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, Biotin carboxylase, ... 著者 Chou, C.Y, Tong, L. 登録日 2011-05-05 公開日 2011-05-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
3RV3	Crystal structure of E.coli biotin carboxylase in complex with two ADP and one Mg ion 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION 著者 Chou, C.Y, Tong, L. 登録日 2011-05-05 公開日 2011-05-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
2YL2	Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain 分子名称: ACETYL-COA CARBOXYLASE 1 著者 Muniz, J.R.C, Froese, D.S, Krysztofinska, E, Vollmar, M, Beltrami, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Oppermann, U. 登録日 2011-05-31 公開日 2011-06-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain To be Published
3TW7	Structure of Rhizobium etli pyruvate carboxylase T882A crystallized without acetyl coenzyme-A 分子名称: CHLORIDE ION, MAGNESIUM ION, Pyruvate carboxylase protein, ... 著者 St Maurice, M, Kumar, S, Lietzan, A.D. 登録日 2011-09-21 公開日 2011-10-12 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
3TW6	Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 St Maurice, M, Kumar, S, Lietzan, A.D. 登録日 2011-09-21 公開日 2011-10-19 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
3U9T	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme 分子名称: Methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit 著者 Huang, C.S, Tong, L. 登録日 2011-10-19 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012
3U9S	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Methylcrotonyl-CoA carboxylase, ... 著者 Huang, C.S, Tong, L. 登録日 2011-10-19 公開日 2011-12-14 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012

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