PDB: 437 件ウェブページステータス検索Chemie searchBIRD

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7Z5Q	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP) 分子名称: Insulin, Insulin A chain, SULFATE ION 著者 van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
7Z5L	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO) 分子名称: GLYCEROL, Insulin A chain, Insulin B chain, ... 著者 van den Elsen, J.M.H, Wahid, A.A, Crennell, C. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
7INS	STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z 分子名称: GENERAL PROTAMINE CHAIN, INSULIN (CHAIN A), INSULIN (CHAIN B), ... 著者 Balschmidt, P, Hansen, F.B, Dodson, E, Dodson, G, Korber, F. 登録日 1991-09-03 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of porcine insulin cocrystallized with clupeine Z. Acta Crystallogr.,Sect.B, 47, 1991
7ELJ	Prion Derived Tetrapeptide Stabilizes Thermolabile Insulin via Conformational Trapping 分子名称: IS1, Insulin A Chain, Insulin B chain 著者 Banerjee, N. 登録日 2021-04-11 公開日 2021-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Prion-derived tetrapeptide stabilizes thermolabile insulin via conformational trapping. Iscience, 24, 2021
7NHU	Crystal structure of desB30 insulin produced by cell free protein synthesis 分子名称: Insulin 著者 Johansson, E. 登録日 2021-02-11 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein. Protein Expr.Purif., 186, 2021
7JP3	Des-B29,B30-insulin 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, PHENOL, ... 著者 Yoder, J, Weiss, M.A, DiMarchi, R, Zaykov, A. 登録日 2020-08-07 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Des-B29,B30-insulin To Be Published
4NIB	Crystal structure of human insulin mutant B20 D-ala, B23 D-ala 分子名称: Insulin A chain, Insulin B chain 著者 Menting, J.G, Lawrence, M.C. 登録日 2013-11-05 公開日 2014-08-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Protective hinge in insulin opens to enable its receptor engagement. Proc.Natl.Acad.Sci.USA, 111, 2014
4P65	Crystal structure of an cyclohexylalanine substituted insulin analog. 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Pandyarajan, V, Wan, Z, Weiss, M.A. 登録日 2014-03-21 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Aromatic Anchor at an Invariant Hormone-Receptor Interface: FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN. J.Biol.Chem., 289, 2014
4RXW	Crystal Structure of the cobalt human insulin derivative 分子名称: COBALT (II) ION, Insulin A chain, Insulin B chain 著者 Prugovecki, B, Ivetic, N, Matkovic-Calogovic, D. 登録日 2014-12-12 公開日 2015-01-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of the cobalt human insulin derivative TO BE PUBLISHED
3LRI	Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I 分子名称: PROTEIN (INSULIN-LIKE GROWTH FACTOR I) 著者 Laajoki, L.G, Francis, G.L, Wallace, J.C, Carver, J.A, Keniry, M.A. 登録日 1999-04-13 公開日 2000-05-23 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I J.Biol.Chem., 275, 2000
2ZP6	Crystal structure of Bovine Insulin (Hexameric form) 分子名称: Insulin A chain, Insulin B chain, ZINC ION 著者 Jaimohan, S.M, Naresh, M.D, Mandal, A.B. 登録日 2008-06-27 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Crystal structure of Bovine Insulin (Hexameric form) To be Published
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
3RTO	Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure 分子名称: Insulin, ZINC ION 著者 Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
5HPR	Insulin with proline analog HyP at position B28 in the T2 state 分子名称: GLYCEROL, Insulin A-Chain, Insulin B-Chain, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
5HQI	Insulin with proline analog HzP at position B28 in the T2 state 分子名称: Insulin A-Chain, Insulin B-Chain 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
4UNH	Human insulin B26Gly mutant crystal structure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION 著者 Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. 登録日 2014-05-28 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
4UNE	Human insulin B26Phe mutant crystal structure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION 著者 Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. 登録日 2014-05-28 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
4UNG	Human insulin B26Asn mutant crystal structure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION 著者 Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. 登録日 2014-05-28 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
5AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE 分子名称: PHENOL, PROTEIN (INSULIN) 著者 O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. 登録日 1998-12-29 公開日 2000-02-28 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
6GNQ	Monoclinic crystalline form of human insulin, complexed with meta-cresol 分子名称: 1,2-ETHANEDIOL, Insulin, M-CRESOL, ... 著者 Margiolaki, I, Karavassili, F, Valmas, A, Dimarogona, M, Giannopoulou, A.E, Fili, S, Schluckebier, G, Norrman, M, Beckers, D, Fitch, A.N. 登録日 2018-05-31 公開日 2019-06-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Monoclinic crystalline form of human insulin, complexed with meta-cresol To Be Published
2ZPP	Neutron crystal structure of cubic insulin at pD9 分子名称: Insulin A chain, Insulin B chain 著者 Ishikawa, T, Tanaka, I, Niimura, N. 登録日 2008-07-26 公開日 2008-10-28 最終更新日 2023-11-01 実験手法 NEUTRON DIFFRACTION (2.5 Å) 主引用文献 An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis Biochem.Biophys.Res.Commun., 376, 2008
6GV0	Insulin glulisine 分子名称: FORMIC ACID, Insulin, ZINC ION 著者 Chayen, N.E, Helliwell, J.R, Solomon-Gamsu, H.V, Govada, L, Morgan, M, Gillis, R.B, Adams, G. 登録日 2018-06-20 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Sci Rep, 11, 2021
5HPU	Insulin with proline analog HyP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin, chain A, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
3T2A	TMAO-grown cubic insulin (porcine) 分子名称: Insulin A chain, Insulin B chain, trimethylamine oxide 著者 Cahn, J, Venkat, M, Marshall, H, Juers, D. 登録日 2011-07-22 公開日 2011-12-28 最終更新日 2012-01-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
5HRQ	Insulin with proline analog HzP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin A-Chain, Insulin B-Chain, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-24 公開日 2017-01-25 最終更新日 2020-01-15 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017

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