6AED
 
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1CDJ
 | | STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 | | 分子名称: | T-CELL SURFACE GLYCOPROTEIN CD4 | | 著者 | Wu, H, Myszka, D, Tendian, S.W, Brouillette, C.G, Sweet, R.W, Chaiken, I.M, Hendrickson, W.A. | | 登録日 | 1996-11-11 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
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1CDH
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1IM9
 | | Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1 bound to its MHC ligand HLA-Cw4 | | 分子名称: | Beta-2 microglobulin, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, CW-4 CW*0401 ALPHA CHAIN, ... | | 著者 | Fan, Q.R, Long, E.O, Wiley, D.C. | | 登録日 | 2001-05-10 | | 公開日 | 2001-05-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex.
Nat.Immunol., 2, 2001
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1RZK
 | | HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | 登録日 | 2003-12-24 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
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4WRL
 | | Structure of the human CSF-1:CSF-1R complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Macrophage colony-stimulating factor 1 receptor, ... | | 著者 | Felix, J, De Munck, S, Elegheert, J, Savvides, S.N. | | 登録日 | 2014-10-24 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
Structure, 23, 2015
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1RZJ
 | | HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | 登録日 | 2003-12-24 | | 公開日 | 2004-02-03 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
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6GRS
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4X4M
 | | Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lu, J, Sun, P.D. | | 登録日 | 2014-12-03 | | 公開日 | 2015-04-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.485 Å) | | 主引用文献 | Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3EJJ
 | | Structure of M-CSF bound to the first three domains of FMS | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Colony stimulating factor-1, Macrophage colony-stimulating factor 1 receptor | | 著者 | Chen, X, Liu, H, Focia, P.J, Shim, A, He, X. | | 登録日 | 2008-09-18 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Proc.Natl.Acad.Sci.USA, 105, 2008
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1IGA
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7T0O
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7T0R
 | | Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ... | | 著者 | Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X. | | 登録日 | 2021-11-30 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
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6ZDX
 | | RIFIN variable region bound to LILRB1 ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... | | 著者 | Harrison, T.E, Higgins, M.K. | | 登録日 | 2020-06-15 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for RIFIN-mediated activation of LILRB1 in malaria.
Nature, 587, 2020
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7QDP
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1ZVO
 | | Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering | | 分子名称: | Immunoglobulin delta heavy chain, myeloma immunoglobulin D lambda | | 著者 | Sun, Z, Almogren, A, Furtado, P.B, Chowdhury, B, Kerr, M.A, Perkins, S.J. | | 登録日 | 2005-06-02 | | 公開日 | 2005-10-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Semi-extended Solution Structure of Human Myeloma Immunoglobulin D Determined by Constrained X-ray Scattering.
J.Mol.Biol., 353, 2005
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7QUH
 | | Siglec-8 in complex with therapeutic Fab AK002. | | 分子名称: | Sialic acid-binding Ig-like lectin 8, Sialic acid-binding immunoglobulin-type lectin | | 著者 | Lenza, M.P, Oyenarte, I, Jimenez Barbero, J, Ereno Orbea, J. | | 登録日 | 2022-01-18 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.867 Å) | | 主引用文献 | Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.
Jacs Au, 3, 2023
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5WY8
 | | Crystal structure of PTP delta Ig1-Ig3 in complex with IL1RAPL1 Ig1-Ig3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | | 著者 | Kim, H.M, Won, S.Y, Kim, D. | | 登録日 | 2017-01-11 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate
Front Mol Neurosci, 10, 2017
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7OL2
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7OL4
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6GRT
 | | Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Paired immunoglobulin-like receptor B, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Vlieg, H.C, Huizinga, E.G, Janssen, B.J.C. | | 登録日 | 2018-06-12 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (4.504 Å) | | 主引用文献 | Structure and flexibility of the extracellular region of the PirB receptor.
J.Biol.Chem., 294, 2019
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6CM3
 | | BG505 SOSIP in complex with sCD4, 17b, 8ANC195 | | 分子名称: | 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, H, Bjorkman, P.J. | | 登録日 | 2018-03-02 | | 公開日 | 2018-10-17 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
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7AW6
 | | The extracellular region of CD33 with bound sialoside analogue P22 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Thompson, A.P, Arrowsmith, C.H, Edwards, A.M, von Delft, F, Bountra, C, Gileadi, O. | | 登録日 | 2020-11-06 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The extracellular region of CD33 with bound sialoside analogue P22
To Be Published
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7K81
 | | KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, Beta-2-microglobulin, ... | | 著者 | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | | 登録日 | 2020-09-24 | | 公開日 | 2020-12-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
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7K80
 | | KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ... | | 著者 | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | | 登録日 | 2020-09-24 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
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