7AW6

The extracellular region of CD33 with bound sialoside analogue P22

Summary for 7AW6

• Entry DOI: 10.2210/pdb7aw6/pdb
• Descriptor: Myeloid cell surface antigen CD33, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, ... (6 entities in total)
• Functional Keywords: receptor, siglec, ig-like, sialic acid, alzheimer's disease, lectin, cell surface antigen, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 59991.55

Authors

Bradshaw, W.J.,Katis, V.L.,Thompson, A.P.,Arrowsmith, C.H.,Edwards, A.M.,von Delft, F.,Bountra, C.,Gileadi, O. (deposition date: 2020-11-06, release date: 2020-12-16, Last modification date: 2024-11-20)

• Primary citation: Bradshaw, W.J.,Katis, V.L.,Thompson, A.P.,Arrowsmith, C.H.,Edwards, A.M.,von Delft, F.,Bountra, C.,Gileadi, O.; The extracellular region of CD33 with bound sialoside analogue P22; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)