7AW6
The extracellular region of CD33 with bound sialoside analogue P22
Summary for 7AW6
Entry DOI | 10.2210/pdb7aw6/pdb |
Descriptor | Myeloid cell surface antigen CD33, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, ... (6 entities in total) |
Functional Keywords | receptor, siglec, ig-like, sialic acid, alzheimer's disease, lectin, cell surface antigen, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 59991.55 |
Authors | Bradshaw, W.J.,Katis, V.L.,Thompson, A.P.,Arrowsmith, C.H.,Edwards, A.M.,von Delft, F.,Bountra, C.,Gileadi, O. (deposition date: 2020-11-06, release date: 2020-12-16, Last modification date: 2024-01-31) |
Primary citation | Bradshaw, W.J.,Katis, V.L.,Thompson, A.P.,Arrowsmith, C.H.,Edwards, A.M.,von Delft, F.,Bountra, C.,Gileadi, O. The extracellular region of CD33 with bound sialoside analogue P22 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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