PDB: 118 件ウェブページステータス検索Chemie searchBIRD

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3QLC	Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide 分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3 著者 Li, H, Patel, D.J. 登録日 2011-02-02 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011
3QO2	Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9 分子名称: 1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8 著者 Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X. 登録日 2011-02-09 公開日 2011-04-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding. J.Mol.Biol., 408, 2011
2RSN	Solution structure of the chromodomain of Chp1 in complex with H3K9me3 peptide 分子名称: Chromo domain-containing protein 1, peptide from Histone H3 著者 Shimojo, H, Nishimura, Y. 登録日 2012-04-18 公開日 2012-08-29 最終更新日 2025-03-26 実験手法 SOLUTION NMR 主引用文献 Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing Mol.Cell, 47, 2012
6VFO	Solution structure of the PHD of mouse UHRF1 (NP95) 分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION 著者 Lemak, A, Houliston, S, Duan, S, Arrowsmith, C.H. 登録日 2020-01-06 公開日 2020-06-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Nucleic Acids Res., 48, 2020
6VEE	Solution structure of the TTD and linker region of mouse UHRF1 (NP95) 分子名称: E3 ubiquitin-protein ligase UHRF1 著者 Lemak, A, Houliston, S, Duan, S, Arrowsmith, C.H. 登録日 2019-12-31 公開日 2020-06-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Nucleic Acids Res., 48, 2020
6VED	Solution structure of the TTD and linker region of UHRF1 分子名称: E3 ubiquitin-protein ligase UHRF1 著者 Lemak, A, Houliston, S, Duan, S, Ong, M.S, Arrowsmith, C.H. 登録日 2019-12-31 公開日 2020-06-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Nucleic Acids Res., 48, 2020
7M5U	Crystal structure of human MPP8 chromodomain in complex with peptidomimetic ligand UNC5246 分子名称: M-phase phosphoprotein 8, UNC5246 著者 Budziszewski, G.R, McGinty, R.K, Waybright, J.M, Norris, J.L, James, L.I. 登録日 2021-03-24 公開日 2021-09-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex. Acs Chem.Biol., 16, 2021
4IUR	crystal structure of SHH1 SAWADEE domain in complex with H3K9me3 peptide 分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... 著者 Patel, D.J, Du, J. 登録日 2013-01-21 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
6SWG	Crystal structure of the TASOR-Periphilin core complex 分子名称: Periphilin-1, Protein TASOR, SULFATE ION 著者 Prigozhin, D.M, Freund, S.M.V, Modis, Y. 登録日 2019-09-20 公開日 2020-08-05 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Periphilin self-association underpins epigenetic silencing by the HUSH complex. Nucleic Acids Res., 48, 2020
6MHA	dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine 分子名称: Heterochromatin protein 1, histone H3 peptide containing trimethyllysine, H3K9me3 著者 Brustad, E.M, Krone, M.W, Albanese, K.I, Waters, M.L. 登録日 2018-09-17 公開日 2019-09-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.497 Å) 主引用文献 Thermodynamic consequences of Tyr to Trp mutations in the cation-pi-mediated binding of trimethyllysine by the HP1 chromodomain Chem Sci, 11, 2020
8QFB	Crystal structure of human MPP8 C-terminal region (residues 565-860) 分子名称: M-phase phosphoprotein 8 著者 Prigozhin, D.M, Modis, Y. 登録日 2023-09-04 公開日 2024-09-11 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Structure and Methyl-lysine Binding Selectivity of the HUSH Complex Subunit MPP8. J.Mol.Biol., 437, 2024
6V2S	Crystal Structure of chromodomain of MPP8 in complex with inhibitor UNC3866 分子名称: M-phase phosphoprotein 8, UNC3866, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2019-11-25 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
6D07	Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide 分子名称: Chromobox protein homolog 1, GLYCEROL, Histone H3.1 著者 Arora, S, Horne, W.S, Islam, K. 登録日 2018-04-10 公開日 2019-04-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions. J.Am.Chem.Soc., 141, 2019
7EF2	Crystal structure of maize SHH2 SAWADEE domain in complex with an H3K9me3 peptide 分子名称: HB transcription factor, Histone H3.2, ZINC ION 著者 Wang, Y, Du, J. 登録日 2021-03-20 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Recognition of H3K9me1 by maize RNA-directed DNA methylation factor SHH2. J Integr Plant Biol, 63, 2021
3G7L	Chromodomain of Chp1 in complex with Histone H3K9me3 peptide 分子名称: ACETIC ACID, Chromo domain-containing protein 1, Histone H3.1/H3.2, ... 著者 Schalch, T, Joshua-Tor, L. 登録日 2009-02-10 公開日 2009-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin Mol.Cell, 34, 2009
2RVN	Solution structure of the chromodomain of HP1a with the phosphorylated N-terminal tail complexed with H3K9me3 peptide 分子名称: 18-mer peptide of Histone H3, Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 最終更新日 2025-03-26 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
5IAY	NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Spacer 著者 Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. 登録日 2016-02-22 公開日 2016-04-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition Nat Commun, 7, 2016
4HOO	Crystal structure of human JMJD2D/KDM4D apoenzyme 分子名称: ACETATE ION, Lysine-specific demethylase 4D, NICKEL (II) ION, ... 著者 Krishnan, S, Trievel, R.C. 登録日 2012-10-22 公開日 2012-11-21 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases. Structure, 21, 2013
9BAP	CryoEM structure of Apo-DIM2 分子名称: DNA (cytosine-5-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Song, J, Shao, Z. 登録日 2024-04-04 公開日 2024-07-24 最終更新日 2025-02-05 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation. Nat Commun, 15, 2024
9BAZ	CryoEM structure of DIM2-HP1 complex 分子名称: DNA (cytosine-5-)-methyltransferase, Heterochromatin protein one, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Song, J, Shao, Z. 登録日 2024-04-05 公開日 2024-07-24 最終更新日 2025-02-05 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation. Nat Commun, 15, 2024
7BU9	Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex 分子名称: H3(K4me3-K9me2) peptide, Spindlin-1 著者 Zhao, F, Li, H. 登録日 2020-04-05 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.502 Å) 主引用文献 Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1. J.Biol.Chem., 295, 2020
7BQZ	Crystal Structure of Spindlin1 bound to H3(K4me3-K9me3) peptide 分子名称: H3(K4me3-K9me3) peptide, Spindlin-1 著者 Zhao, F, Li, H. 登録日 2020-03-26 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1. J.Biol.Chem., 295, 2020
3AVR	Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Histone H3, ... 著者 Sengoku, T, Yokoyama, S. 登録日 2011-03-07 公開日 2011-10-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A Genes Dev., 25, 2011
3AVS	Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 6A, ... 著者 Sengoku, T, Yokoyama, S. 登録日 2011-03-07 公開日 2011-10-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A Genes Dev., 25, 2011
3U5M	Crystal structure of TRIM33 PHD-Bromo in the free state 分子名称: CALCIUM ION, E3 ubiquitin-protein ligase TRIM33, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2011-10-11 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 A poised chromatin platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147, 2011

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