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8QFB

Crystal structure of human MPP8 C-terminal region (residues 565-860)

Summary for 8QFB
Entry DOI10.2210/pdb8qfb/pdb
DescriptorM-phase phosphoprotein 8 (1 entity in total)
Functional Keywordstranscriptional regulation, epigenetic silencing, antiviral response, genome stability, histone h3 lysine 9 methylation (h3k9me3), transposable element (te), long interspersed nuclear element-1 (line-1), rna-binding protein, human silencing hub (hush) complex, transcription
Biological sourceHomo sapiens (human)
Total number of polymer chains8
Total formula weight295360.44
Authors
Prigozhin, D.M.,Modis, Y. (deposition date: 2023-09-04, release date: 2024-09-11)
Primary citationNikolopoulos, N.,Oda, S.,Prigozhin, D.M.,Modis, Y.
Structure and methyl-lysine binding selectivity of the HUSH complex subunit MPP8
to be published,
Experimental method
X-RAY DIFFRACTION (3.04 Å)
Structure validation

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PDB entries from 2024-10-09

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