2C6G
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![BU of 2c6g by Molmil](/molmil-images/mine/2c6g) | Membrane-bound glutamate carboxypeptidase II (GCPII) with bound glutamate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Mesters, J.R, Barinka, C, Li, W, Tsukamoto, T, Majer, P, Slusher, B.S, Konvalinka, J, Hilgenfeld, R. | 登録日 | 2005-11-09 | 公開日 | 2006-02-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer. EMBO J., 25, 2006
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1TV2
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![BU of 1tv2 by Molmil](/molmil-images/mine/1tv2) | Crystal structure of the hydroxylamine MtmB complex | 分子名称: | 5-HYDROXYAMINO-3-METHYL-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1 | 著者 | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | 登録日 | 2004-06-26 | 公開日 | 2004-10-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid Chem.Biol., 11, 2004
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3AXG
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![BU of 3axg by Molmil](/molmil-images/mine/3axg) | Structure of 6-aminohexanoate-oligomer hydrolase | 分子名称: | Endotype 6-aminohexanoat-oligomer hydrolase, SODIUM ION | 著者 | Negoro, S, Shibata, N, Tanaka, Y, Yasuhira, K, Shibata, H, Hashimoto, H, Lee, Y.H, Ohshima, S, Santa, R, Mochiji, K, Goto, Y, Ikegami, T, Nagai, K, Kato, D, Takeo, M, Higuchi, Y. | 登録日 | 2011-04-04 | 公開日 | 2011-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis J.Biol.Chem., 287, 2012
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5G2B
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![BU of 5g2b by Molmil](/molmil-images/mine/5g2b) | Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-008 | 分子名称: | CLASS 1 PHOSPHODIESTERASE PDEB1, FORMIC ACID, GLYCEROL, ... | 著者 | Singh, A.K, Anthonyrajah, E.S, Brown, D.G. | 登録日 | 2016-04-07 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
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8J1V
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![BU of 8j1v by Molmil](/molmil-images/mine/8j1v) | |
7EK4
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![BU of 7ek4 by Molmil](/molmil-images/mine/7ek4) | prawn ferritin to coordinate with heavy metal ions | 分子名称: | FE (III) ION, Ferritin, MERCURY (II) ION | 著者 | Wang, Y, Zang, J. | 登録日 | 2021-04-03 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin. Int J Mol Sci, 22, 2021
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5GGU
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![BU of 5ggu by Molmil](/molmil-images/mine/5ggu) | Crystal structure of tremelimumab Fab | 分子名称: | heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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7EK7
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![BU of 7ek7 by Molmil](/molmil-images/mine/7ek7) | prawn ferritin to coordinate with heavy metal ions | 分子名称: | Ferritin, MERCURY (II) ION | 著者 | Wang, Y, Zang, J. | 登録日 | 2021-04-04 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin. Int J Mol Sci, 22, 2021
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7EK5
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![BU of 7ek5 by Molmil](/molmil-images/mine/7ek5) | prawn ferritin to coordinate with heavy metal ions | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin | 著者 | Wang, Y, Zang, J. | 登録日 | 2021-04-03 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin. Int J Mol Sci, 22, 2021
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7OAO
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![BU of 7oao by Molmil](/molmil-images/mine/7oao) | Nanobody C5 bound to RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, C5 nanobody, ... | 著者 | Naismith, J.H, Mikolajek, H. | 登録日 | 2021-04-19 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19. Nat Commun, 12, 2021
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7OAQ
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4MWJ
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![BU of 4mwj by Molmil](/molmil-images/mine/4mwj) | Anhui N9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | 登録日 | 2013-09-25 | 公開日 | 2013-11-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
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4MWW
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![BU of 4mww by Molmil](/molmil-images/mine/4mww) | Shanghai N9-oseltamivir carboxylate | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | 登録日 | 2013-09-25 | 公開日 | 2013-11-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
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7OAP
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![BU of 7oap by Molmil](/molmil-images/mine/7oap) | Nanobody H3 AND C1 bound to RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C1 nanobody, CHLORIDE ION, ... | 著者 | Naismith, J.H, Mikolajek, H. | 登録日 | 2021-04-19 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19. Nat Commun, 12, 2021
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8J1T
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2C65
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![BU of 2c65 by Molmil](/molmil-images/mine/2c65) | MAO inhibition by rasagiline analogues | 分子名称: | (1R)-4-({[ETHYL(METHYL)AMINO]CARBONYL}OXY)-N-METHYL-N-[(1E)-PROP-2-EN-1-YLIDENE]INDAN-1-AMINIUM, AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Binda, C, Hubalek, F, Li, M, Herzig, Y, Sterling, J, Edmondson, D.E, Mattevi, A. | 登録日 | 2005-11-07 | 公開日 | 2006-01-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis. J.Med.Chem., 48, 2005
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1TV4
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![BU of 1tv4 by Molmil](/molmil-images/mine/1tv4) | Crystal structure of the sulfite MtmB complex | 分子名称: | 3-METHYL-5-SULFO-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1, SULFATE ION | 著者 | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | 登録日 | 2004-06-26 | 公開日 | 2004-10-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid Chem.Biol., 11, 2004
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7OAN
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![BU of 7oan by Molmil](/molmil-images/mine/7oan) | Nanobody C5 bound to Spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Naismith, J.H, Weckener, M. | 登録日 | 2021-04-19 | 公開日 | 2021-08-11 | 最終更新日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19. Nat Commun, 12, 2021
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7OFV
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![BU of 7ofv by Molmil](/molmil-images/mine/7ofv) | NMR-guided design of potent and selective EphA4 agonistic ligands | 分子名称: | ACETATE ION, EphA4 agonist ligand, Ephrin type-A receptor 4 | 著者 | Ganichkin, O.M, Craig, T.K, Baggio, C, Pellecchia, M. | 登録日 | 2021-05-05 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands. J.Med.Chem., 64, 2021
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7OAY
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![BU of 7oay by Molmil](/molmil-images/mine/7oay) | Nanobody F2 bound to RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F2 nanobody, Spike protein S1 | 著者 | Naismith, J.H, Mikolajek, H. | 登録日 | 2021-04-20 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19. Nat Commun, 12, 2021
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2YE2
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![BU of 2ye2 by Molmil](/molmil-images/mine/2ye2) | HSP90 inhibitors and drugs from fragment and virtual screening | 分子名称: | HEAT SHOCK PROTEIN HSP 90-ALPHA, METHYL 2-(3,5-DIHYDROXYPHENYL)ETHANOATE, SULFATE ION | 著者 | Roughley, S.D, Hubbard, R.E, Baker, L.M. | 登録日 | 2011-03-25 | 公開日 | 2011-06-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | How Well Can Fragments Explore Accessed Chemical Space? a Case Study from Heat Shock Protein 90. J.Med.Chem., 54, 2011
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7OAU
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![BU of 7oau by Molmil](/molmil-images/mine/7oau) | |
2YED
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![BU of 2yed by Molmil](/molmil-images/mine/2yed) | |
2YHI
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![BU of 2yhi by Molmil](/molmil-images/mine/2yhi) | Trypanosoma brucei PTR1 in complex with inhibitor WH16 | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... | 著者 | Nerini, E, Dawson, A, Hunter, W.N, Costi, M.P. | 登録日 | 2011-05-03 | 公開日 | 2012-05-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery. ACS Omega, 2, 2017
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5GGS
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![BU of 5ggs by Molmil](/molmil-images/mine/5ggs) | PD-1 in complex with pembrolizumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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