7OFV

NMR-guided design of potent and selective EphA4 agonistic ligands

Summary for 7OFV

• Entry DOI: 10.2210/pdb7ofv/pdb
• Descriptor: Ephrin type-A receptor 4, EphA4 agonist ligand, ACETATE ION, ... (4 entities in total)
• Functional Keywords: epha4, 150d4, ephrin, rtk, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 22275.30

Authors

Ganichkin, O.M.,Craig, T.K.,Baggio, C.,Pellecchia, M. (deposition date: 2021-05-05, release date: 2021-08-11, Last modification date: 2024-01-31)

• Primary citation: Baggio, C.,Kulinich, A.,Dennys, C.N.,Rodrigo, R.,Meyer, K.,Ethell, I.,Pellecchia, M.; NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.; J.Med.Chem., 64:11229-11246, 2021; PubMed: 34293864; DOI: 10.1021/acs.jmedchem.1c00608

Experimental method

X-RAY DIFFRACTION (1.43 Å)