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2QON
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Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742A triple mutant
分子名称: Ephrin receptor, GLYCEROL
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOO
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Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742F triple mutant
分子名称: Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOP
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Crystal structure of the transcriptional regulator AcrR from Escherichia coli
分子名称: HTH-type transcriptional regulator acrR
著者Li, M, Gu, R, Su, C.-C, McDermott, G, Yu, E.W.
登録日2007-07-20
公開日2008-02-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the transcriptional regulator AcrR from Escherichia coli.
J.Mol.Biol., 374, 2007
2QOQ
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Human EphA3 kinase and juxtamembrane region, base, AMP-PNP bound structure
分子名称: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Loppnau, P, Allali-Hassani, A, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-10-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOR
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Crystal structure of Plasmodium vivax guanylate kinase
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, PYROPHOSPHATE 2-
著者Merritt, E.A, Le Trong, I, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2007-07-20
公開日2007-08-07
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Plasmodium vivax guanylate kinase.
To be Published
2QOS
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Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8
分子名称: Complement component 8, gamma polypeptide, Complement component C8 alpha chain
著者Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L.
登録日2007-07-20
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding.
Mol.Immunol., 45, 2008
2QP2
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Structure of a MACPF/perforin-like protein
分子名称: CALCIUM ION, Unknown protein
著者Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C.
登録日2007-07-22
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
2QP3
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Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1
分子名称: (3Beta,5alpha)-3-Hydroxyandrostan-17-one, Bile salt sulfotransferase
著者Hsieh, Y.C.
登録日2007-07-23
公開日2008-07-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1)
Mol.Pharmacol., 73, 2008
2QP4
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Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1
分子名称: (3Beta,5alpha)-3-Hydroxyandrostan-17-one, Bile salt sulfotransferase
著者Hsieh, Y.C.
登録日2007-07-23
公開日2008-07-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1)
Mol.Pharmacol., 73, 2008
2QP6
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The crystal structure of the complex of hcaII with a bioreductive antitumor derivative
分子名称: 2-chloro-5-nitrobenzenesulfonamide, CHLORIDE ION, Carbonic anhydrase 2, ...
著者D'Ambrosio, K, De Simone, G.
登録日2007-07-23
公開日2008-06-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Carbonic Anhydrase Inhibitors: Bioreductive Nitro-Containing Sulfonamides with Selectivity for Targeting the Tumor Associated Isoforms IX and XII.
J.Med.Chem., 51, 2008
2QP8
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Structure of BACE Bound to SCH734723
分子名称: Beta-secretase 1, D(-)-TARTARIC ACID, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-[(2R,4S)-4-ETHOXYPIPERIDIN-2-YL]-2-HYDROXYETHYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE
著者Strickland, C.O, Iserloh, U.
登録日2007-07-23
公開日2008-03-11
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Potent pyrrolidine- and piperidine-based BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
2QP9
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Crystal Structure of S.cerevisiae Vps4
分子名称: CADMIUM ION, SULFATE ION, Vacuolar protein sorting-associated protein 4
著者Xiao, J, Xu, Z.
登録日2007-07-23
公開日2007-10-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4.
J.Mol.Biol., 374, 2007
2QPA
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Crystal Structure of S.cerevisiae Vps4 in the presence of ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Vacuolar protein sorting-associated protein 4
著者Xiao, J, Xu, Z.
登録日2007-07-23
公開日2007-10-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4.
J.Mol.Biol., 374, 2007
2QPD
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An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus
分子名称: COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ...
著者Liu, B, Luna, V.M, Chen, Y, Stout, C.D, Fee, J.A.
登録日2007-07-23
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献An unexpected outcome of surface engineering an integral membrane protein: improved crystallization of cytochrome ba(3) from Thermus thermophilus.
Acta Crystallogr.,Sect.F, 63, 2007
2QPE
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An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus
分子名称: COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ...
著者Liu, B, Luna, V.M, Chen, Y, Stout, C.D, Fee, J.A.
登録日2007-07-23
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献An unexpected outcome of surface engineering an integral membrane protein: improved crystallization of cytochrome ba(3) from Thermus thermophilus.
Acta Crystallogr.,Sect.F, 63, 2007
2QPF
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Crystal Structure of Mouse Transthyretin
分子名称: Transthyretin
著者Reixach, N, Foss, T.R, Santelli, E, Pascual, J, Kelly, J.W, Buxbaum, J.N.
登録日2007-07-23
公開日2007-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Human-Murine Transthyretin Heterotetramers Are Kinetically Stable and Non-amyloidogenic: A LESSON IN THE GENERATION OF TRANSGENIC MODELS OF DISEASES INVOLVING OLIGOMERIC PROTEINS.
J.Biol.Chem., 283, 2008
2QPJ
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Human NEP complexed with a bifunctional NEP/DPP IV inhibitor
分子名称: (2S)-2-({(2S)-3-[(R)-[(1R)-1-({(4S)-4-amino-5-[(2S)-2-cyanopyrrolidin-1-yl]-5-oxopentanoyl}amino)ethyl](hydroxy)phosphoryl]-2-benzylpropanoyl}amino)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Neprilysin, ...
著者Oefner, C, Dale, G.E.
登録日2007-07-24
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV.
Acta Crystallogr.,Sect.D, 63, 2007
2QPK
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Crystal structure of the complex of bovine lactoperoxidase with salicylhydroxamic acid at 2.34 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, IODIDE ION, ...
著者Singh, A.K, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
登録日2007-07-24
公開日2007-08-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structure of bovine lactoperoxidase with a partially linked heme moiety at 1.98 angstrom resolution.
Biochim.Biophys.Acta, 1865, 2017
2QPL
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Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue
分子名称: 4-amino-7-methylpyrazolo[1,5-a][1,3,5]triazin-2(1H)-one, MAGNESIUM ION, Purine nucleoside phosphorylase, ...
著者Pereira, H.M, Berdini, V, Cleasby, A, Garratt, R.C.
登録日2007-07-24
公開日2007-12-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue.
Febs Lett., 581, 2007
2QPM
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Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with benzylurea inhibitor CPBU
分子名称: 1-benzyl-3-(2-chloropyridin-4-yl)urea, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Briozzo, P.
登録日2007-07-24
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Phenyl- and benzylurea cytokinins as competitive inhibitors of cytokinin oxidase/dehydrogenase: a structural study.
Biochimie, 92, 2010
2QPN
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GES-1 beta-lactamase
分子名称: Beta-lactamase GES-1, SULFATE ION
著者Smith, C.A, Caccamo, M, Kantardjieff, K.A, Vakulenko, S.
登録日2007-07-24
公開日2008-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure of GES-1 at atomic resolution: insights into the evolution of carbapenamase activity in the class A extended-spectrum beta-lactamases.
Acta Crystallogr.,Sect.D, 63, 2007
2QPO
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Thermotoga Maritima Thymidine Kinase in the apo form
分子名称: SULFATE ION, Thymidine kinase, ZINC ION
著者Segura-Pena, D, Lichter, J, Trani, M, Konrad, M, Lavie, A, Lutz, S.
登録日2007-07-24
公開日2007-10-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.
Structure, 15, 2007
2QPP
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Crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme
分子名称: Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE
著者Bianchetti, C.M, Bingman, C.A, Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-07-24
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2.
J.Biol.Chem., 282, 2007
2QPQ
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Structure of Bug27 from Bordetella pertussis
分子名称: CITRIC ACID, protein Bug27
著者Herrou, J, Bompard, C.
登録日2007-07-25
公開日2007-08-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure-based mechanism of ligand binding for periplasmic solute-binding protein of the Bug family.
J.Mol.Biol., 373, 2007
2QPS
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"Sugar tongs" mutant Y380A in complex with acarbose
分子名称: Alpha-amylase type A isozyme, CALCIUM ION
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007

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