2QPF

Crystal Structure of Mouse Transthyretin

Summary for 2QPF

• Entry DOI: 10.2210/pdb2qpf/pdb
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: transport protein, amyloidogenesis, tetramer, glycoprotein, hormone, retinol-binding, secreted, thyroid hormone, vitamin a
• Biological source: Mus musculus (house mouse)
• Cellular location: Secreted: P07309
• Total number of polymer chains: 8
• Total formula weight: 110683.37

Authors

Reixach, N.,Foss, T.R.,Santelli, E.,Pascual, J.,Kelly, J.W.,Buxbaum, J.N. (deposition date: 2007-07-23, release date: 2007-11-27, Last modification date: 2023-11-15)

• Primary citation: Reixach, N.,Foss, T.R.,Santelli, E.,Pascual, J.,Kelly, J.W.,Buxbaum, J.N.; Human-Murine Transthyretin Heterotetramers Are Kinetically Stable and Non-amyloidogenic: A LESSON IN THE GENERATION OF TRANSGENIC MODELS OF DISEASES INVOLVING OLIGOMERIC PROTEINS.; J.Biol.Chem., 283:2098-2107, 2008; PubMed: 18006495; DOI: 10.1074/jbc.M708028200

Experimental method

X-RAY DIFFRACTION (2.05 Å)