2QOO

Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742F triple mutant

Summary for 2QOO

Entry DOI	10.2210/pdb2qoo/pdb
Related	2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOF 2QOI 2QOK 2QOL 2QON 2QOQ
Descriptor	Ephrin receptor (2 entities in total)
Functional Keywords	receptor tyrosine kinase, juxtamembrane segment, structural genomics, mutant, structural genomics consortium, sgc, atp-binding, nucleotide-binding, phosphorylation, transferase, transmembrane, tyrosine-protein kinase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	41915.86
Authors	Davis, T.,Walker, J.R.,Newman, E.M.,Mackenzie, F.,Butler-Cole, C.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-07-20, release date: 2007-08-28, Last modification date: 2023-08-30)
Primary citation	Davis, T.L.,Walker, J.R.,Loppnau, P.,Butler-Cole, C.,Allali-Hassani, A.,Dhe-Paganon, S. Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16:873-884, 2008 Cited by PubMed: 18547520 DOI: 10.1016/j.str.2008.03.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation