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7SNC
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Pacifastin related protease inhibitors
分子名称: Protease inhibitor
著者Gewe, M.M, Strong, R.K.
登録日2021-10-27
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
6F3V
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Backbone structure of bradykinin (BK) peptide bound to human Bradykinin 2 Receptor (B2R) determined by MAS SSNMR
分子名称: Bradykinin (BK)
著者Mao, J, Lopez, J.J, Shukla, A.K, Kuenze, G, Meiler, J, Schwalbe, H, Michel, H, Glaubitz, C.
登録日2017-11-29
公開日2018-01-10
最終更新日2024-06-19
実験手法SOLID-STATE NMR
主引用文献The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.
Nat. Chem. Biol., 14, 2018
6F3W
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Backbone structure of free bradykinin (BK) in DDM/CHS detergent micelle determined by MAS SSNMR
分子名称: Kininogen-1
著者Mao, J, Lopez, J.J, Shukla, A.K, Kuenze, G, Meiler, J, Schwalbe, H, Michel, H, Glaubitz, C.
登録日2017-11-29
公開日2018-01-10
最終更新日2024-06-19
実験手法SOLID-STATE NMR
主引用文献The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.
Nat. Chem. Biol., 14, 2018
2IWT
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Thioredoxin h2 (HvTrxh2) in a mixed disulfide complex with the target protein BASI
分子名称: ALPHA-AMYLASE/SUBTILISIN INHIBITOR, CITRATE ANION, THIOREDOXIN H ISOFORM 2
著者Maeda, K, Hagglund, P, Finnie, C, Svensson, B, Henriksen, A.
登録日2006-07-04
公開日2006-11-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for Target Protein Recognition by the Protein Disulfide Reductase Thioredoxin.
Structure, 14, 2006
2J5K
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2.0 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui (radiation damage series)
分子名称: CHLORIDE ION, MALATE DEHYDROGENASE
著者Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
登録日2006-09-18
公開日2006-09-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
2J5R
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2.25 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after second radiation burn (radiation damage series)
分子名称: CHLORIDE ION, MALATE DEHYDROGENASE
著者Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
登録日2006-09-19
公開日2006-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
2J5Q
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2.15 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after first radiation burn (radiation damage series)
分子名称: CHLORIDE ION, MALATE DEHYDROGENASE
著者Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
登録日2006-09-19
公開日2006-09-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
8CR1
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Homo sapiens Get1/Get2 heterotetramer in complex with a Get3 dimer
分子名称: ATPase ASNA1, Guided entry of tail-anchored proteins factor CAMLG,Guided entry of tail-anchored proteins factor 1,GET2-GET1, ZINC ION
著者McDowell, M.A, Heimes, M, Wild, K, Sinning, I.
登録日2023-03-07
公開日2023-11-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The GET insertase exhibits conformational plasticity and induces membrane thinning.
Nat Commun, 14, 2023
8ERX
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Structure of chimeric HLA-A*11:01-A*02:01 bound to HIV-1 RT peptide
分子名称: Beta-2-microglobulin, HIV-1 RT, HLA-A*02:01
著者Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G.
登録日2022-10-13
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules.
Front Immunol, 14, 2023
8GW7
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AtSLAC1 6D mutant in open state
分子名称: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment)
著者Lee, Y, Lee, S.
登録日2022-09-16
公開日2023-11-15
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
7F8T
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Re-refinement of the 2XRY X-ray structure of archaeal class II CPD photolyase from Methanosarcina mazei
分子名称: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Maestre-Reyna, M, Yang, C.-H, Huang, W.C, Nango, E, Gusti-Ngurah-Putu, E.-P, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Sugahara, M, Owada, S, Joti, Y, Tanaka, R, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D.
登録日2021-07-02
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme.
Nat.Chem., 14, 2022
7FAB
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CRYSTAL STRUCTURE OF HUMAN IMMUNOGLOBULIN FRAGMENT FAB NEW REFINED AT 2.0 ANGSTROMS RESOLUTION
分子名称: IGG1-LAMBDA NEW FAB (HEAVY CHAIN), IGG1-LAMBDA NEW FAB (LIGHT CHAIN)
著者Saul, F, Poljak, R.J.
登録日1991-11-20
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human immunoglobulin fragment Fab New refined at 2.0 A resolution.
Proteins, 14, 1992
8A58
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X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
分子名称: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
著者James, L.C, Kiss, L.
登録日2022-06-14
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
7ZM5
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Structure of Mossman virus receptor binding protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein
著者Stelfox, A.J, Bowden, T.A, Rissanen, I, Harlos, K.
登録日2022-04-19
公開日2023-09-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein.
Mbio, 14, 2023
8B2N
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Potempin A (PotA) from Tannerella forsythia in complex with the catalytic domain of human MMP-12
分子名称: CALCIUM ION, Macrophage metalloelastase, Tannerella forsythia potempin A (PotA), ...
著者Potempa, J, Ksiazek, M, Goulas, T, Cuppari, A, Rodriguez-Banqueri, A, Arolas, J.L, Lopez-Pelegrin, M, Garcia-Ferrer, I, Guevara, T.
登録日2022-09-14
公開日2022-12-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Chem Sci, 14, 2023
8B2Q
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Matrix-metallopeptidase inhibitor Potempin A (PotA) from Tannerella forsythia in complex with T. forsythia karilysin.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Potempa, J, Ksiazek, M, Goulas, T, Cuppari, A, Rodriguez-Banqueri, A, Arolas, J.L, Lopez-Pelegrin, M, Garcia-Ferrer, I, Guevara, T.
登録日2022-09-14
公開日2022-12-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Chem Sci, 14, 2023
8B2M
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Matrix-metallopeptidase inhibitor Potempin A (PotA) from Tannerella forsythia
分子名称: NICKEL (II) ION, Tannerella forsythia Potempin A (PotA)
著者Potempa, J, Ksiazek, M, Goulas, T, Cuppari, A, Rodriguez-Banqueri, A, Arolas, J.L, Lopez-Pelegrin, M, Garcia-Ferrer, I, Guevara, T.
登録日2022-09-14
公開日2022-12-21
最終更新日2023-02-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Chem Sci, 14, 2023
8AFA
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Cryo-EM structure of a substrate-bound glutamate transporter homologue GltTk encapsulated within a nanodisc
分子名称: ASPARTIC ACID, Proton/glutamate symporter, SDF family
著者Whittaker, J.J, Guskov, A.
登録日2022-07-16
公開日2023-04-05
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Mutation in glutamate transporter homologue GltTk provides insights into pathologic mechanism of episodic ataxia 6.
Nat Commun, 14, 2023
6MVM
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LasR LBD L130F:3OC14HSL complex
分子名称: 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide, Transcriptional regulator LasR
著者Paczkowski, J.E, Bassler, B.L.
登録日2018-10-26
公開日2019-01-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.
Acs Chem.Biol., 14, 2019
8X71
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Crystal structure of Peroxiredoxin I in complex with compound 19-064
分子名称: Peroxiredoxin-1, methyl 3-[[(2~{R},4~{a}~{S},6~{a}~{R},6~{a}~{S},14~{a}~{S},14~{b}~{R})-2,4~{a},6~{a},6~{a},9,14~{a}-hexamethyl-10-oxidanyl-11-oxidanylidene-1,3,4,5,6,13,14,14~{b}-octahydropicen-2-yl]carbamoylamino]oxetane-3-carboxylate
著者Zhang, H, Luo, C.
登録日2023-11-22
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors.
J.Med.Chem., 67, 2024
7O0W
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Cryo-EM structure of the RC-dLH complex (model_1b) from Gemmatimonas phototrophica at 2.47 A
分子名称: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
著者Qian, P, Koblizek, M.
登録日2021-03-27
公開日2022-03-02
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.47 Å)
主引用文献2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
7O0U
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Cryo-EM structure (model_1a) of the RC-dLH complex from Gemmatimonas phototrophica at 2.4 A
分子名称: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
著者Qian, P, Koblizek, M.
登録日2021-03-27
公開日2022-03-02
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.35 Å)
主引用文献2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
7O0X
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Cryo-EM structure (model_2b) of the RC-dLH complex from Gemmatimonas phototrophica at 2.44 A
分子名称: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
著者Qian, P, Koblizek, M.
登録日2021-03-28
公開日2022-03-02
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
7O0V
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Cryo-EM structure (model_2a) of the RC-dLH complex from Gemmatimonas phototrophica at 2.5 A
分子名称: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
著者Qian, P, Koblizek, M.
登録日2021-03-27
公開日2022-03-02
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
1KB9
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YEAST CYTOCHROME BC1 COMPLEX
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ...
著者Lange, C, Nett, J.H, Trumpower, B.L, Hunte, C.
登録日2001-11-05
公開日2002-09-18
最終更新日2011-08-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献SPECIFIC ROLES OF PROTEIN-PHOSPHOLIPID INTERACTIONS IN THE YEAST CYTOCHROME BC1 COMPLEX STRUCTURE
EMBO J., 20, 2001

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