8AFA

Cryo-EM structure of a substrate-bound glutamate transporter homologue GltTk encapsulated within a nanodisc

Summary for 8AFA

Entry DOI	10.2210/pdb8afa/pdb
EMDB information	15393
Descriptor	Proton/glutamate symporter, SDF family, ASPARTIC ACID (2 entities in total)
Functional Keywords	glutamate, transporter, mutant, nanodisc, transport protein
Biological source	Thermococcus kodakarensis
Total number of polymer chains	3
Total formula weight	140635.63
Authors	Whittaker, J.J.,Guskov, A. (deposition date: 2022-07-16, release date: 2023-04-05, Last modification date: 2023-04-12)
Primary citation	Colucci, E.,Anshari, Z.R.,Patino-Ruiz, M.F.,Nemchinova, M.,Whittaker, J.,Slotboom, D.J.,Guskov, A. Mutation in glutamate transporter homologue GltTk provides insights into pathologic mechanism of episodic ataxia 6. Nat Commun, 14:1799-1799, 2023 Cited by PubMed: 37002226 DOI: 10.1038/s41467-023-37503-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.16 Å)

Structure validation