6MVM
LasR LBD L130F:3OC14HSL complex
Summary for 6MVM
Entry DOI | 10.2210/pdb6mvm/pdb |
Descriptor | Transcriptional regulator LasR, 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide (3 entities in total) |
Functional Keywords | transcriptional activator protein, 3-oxo-n-(2-oxooxolan-3-yl)tetradecanamide, transcription |
Biological source | Pseudomonas aeruginosa (strain UCBPP-PA14) |
Total number of polymer chains | 2 |
Total formula weight | 37091.92 |
Authors | Paczkowski, J.E.,Bassler, B.L. (deposition date: 2018-10-26, release date: 2019-01-16, Last modification date: 2023-10-11) |
Primary citation | Paczkowski, J.E.,McCready, A.R.,Cong, J.P.,Li, Z.,Jeffrey, P.D.,Smith, C.D.,Henke, B.R.,Hughson, F.M.,Bassler, B.L. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14:378-389, 2019 Cited by PubMed: 30763066DOI: 10.1021/acschembio.8b00971 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.895 Å) |
Structure validation
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