8A58

X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W

Summary for 8A58

Entry DOI	10.2210/pdb8a58/pdb
Descriptor	Ubiquitin-conjugating enzyme E2 W, E3 ubiquitin-protein ligase TRIM21, ZINC ION, ... (4 entities in total)
Functional Keywords	e3 ubiquitin ligase, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	54514.20
Authors	James, L.C.,Kiss, L. (deposition date: 2022-06-14, release date: 2023-04-26, Last modification date: 2024-02-07)
Primary citation	Kiss, L.,Rhinesmith, T.,Luptak, J.,Dickson, C.F.,Weidenhausen, J.,Smyly, S.,Yang, J.C.,Maslen, S.L.,Sinning, I.,Neuhaus, D.,Clift, D.,James, L.C. Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Nat Commun, 14:2160-2160, 2023 Cited by PubMed: 37061529 DOI: 10.1038/s41467-023-37504-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation