8A58
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Ubiquitin-conjugating enzyme E2 W | polymer | 153 | 17616.2 | 2 | UniProt (Q96B02) Pfam (PF00179) | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme W,N-terminal E2 ubiquitin-conjugating enzyme,N-terminus-conjugating E2,Ubiquitin carrier protein W,Ubiquitin-conjugating enzyme 16,UBC-16,Ubiquitin-protein ligase W |
| 2 | B, C (C, D) | E3 ubiquitin-protein ligase TRIM21 | polymer | 85 | 9510.1 | 2 | UniProt (P19474) Pfam (PF00097) | Homo sapiens (human) | 52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,RING finger protein 81,RING-type E3 ubiquitin transferase TRIM21,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21 |
| 3 | E, F, G, H (C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | I, J, K, L (A, C, D, B) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 151 (UniProt: Q96B02)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Lys 67 | Asp 67 | conflict |
| Lys 91 | Cys 91 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54252.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 54514.2 |
