Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8A58

X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W

Functional Information from GO Data
ChainGOidnamespacecontents
A0000209biological_processprotein polyubiquitination
A0004842molecular_functionubiquitin-protein transferase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0006281biological_processDNA repair
A0006513biological_processprotein monoubiquitination
A0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
A0016567biological_processprotein ubiquitination
A0016740molecular_functiontransferase activity
A0031625molecular_functionubiquitin protein ligase binding
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0061631molecular_functionubiquitin conjugating enzyme activity
A0070979biological_processprotein K11-linked ubiquitination
A0071218biological_processcellular response to misfolded protein
A0140374biological_processantiviral innate immune response
A1904262biological_processnegative regulation of TORC1 signaling
B0000209biological_processprotein polyubiquitination
B0004842molecular_functionubiquitin-protein transferase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0006281biological_processDNA repair
B0006513biological_processprotein monoubiquitination
B0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
B0016567biological_processprotein ubiquitination
B0016740molecular_functiontransferase activity
B0031625molecular_functionubiquitin protein ligase binding
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0061631molecular_functionubiquitin conjugating enzyme activity
B0070979biological_processprotein K11-linked ubiquitination
B0071218biological_processcellular response to misfolded protein
B0140374biological_processantiviral innate immune response
B1904262biological_processnegative regulation of TORC1 signaling
C0004842molecular_functionubiquitin-protein transferase activity
C0016567biological_processprotein ubiquitination
C0046872molecular_functionmetal ion binding
D0004842molecular_functionubiquitin-protein transferase activity
D0016567biological_processprotein ubiquitination
D0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00518
Number of Residues10
DetailsZF_RING_1 Zinc finger RING-type signature. CgHsFCqeCI
ChainResidueDetails
CCYS31-ILE40

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues78
DetailsZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175
ChainResidueDetails
CCYS16-ARG55
DCYS16-ARG55

site_idSWS_FT_FI2
Number of Residues4
DetailsCROSSLNK: Peptide (Met-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23560854
ChainResidueDetails
AMET1
BMET1

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon