PDB: 236963 件ウェブページステータス検索Chemie searchBIRD

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5O76	Structure of phosphoY371 c-CBL in complex with ZAP70-peptide and UbV.pCBL ubiquitin variant 分子名称: CALCIUM ION, E3 ubiquitin-protein ligase CBL, Tyrosine protein kinase ZAP70 peptide, ... 著者 Gabrielsen, M, Buetow, L, Huang, D.T. 登録日 2017-06-08 公開日 2017-11-01 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.473 Å) 主引用文献 A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68, 2017
7LK0	Ornithine Aminotransferase (OAT) cocrystallized with its potent inhibitor - (S)-3-amino-4,4-difluorocyclopent-1-enecarboxylic acid (SS-1-148) 分子名称: (1R,3S)-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-oxocyclopentane-1-carboxylic acid, Ornithine aminotransferase, mitochondrial 著者 Butrin, A, Shen, S, Liu, D, Silverman, R. 登録日 2021-02-01 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Turnover and Inactivation Mechanisms for ( S )-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. J.Am.Chem.Soc., 143, 2021
3EUD	Structure of the CS domain of the essential H/ACA RNP assembly protein Shq1p 分子名称: Protein SHQ1 著者 Singh, M, Cascio, D, Gonzales, F.A, Heckmann, N, Chanfreau, G, Feigon, J. 登録日 2008-10-09 公開日 2008-11-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1. J.Biol.Chem., 284, 2009
4PHM	The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids 分子名称: 3-(5-bromo-1H-indol-3-yl)-2-thioxopropanoic acid, CALCIUM ION, Calpain small subunit 1 著者 Rizkallah, P.J, Allemann, R.K, Adams, S.E, Miller, D.J, Hallett, M.B. 登録日 2014-05-06 公開日 2014-08-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
5OES	The structure of a glutathione synthetase (StGSS1) from Solanum tuberosum in ADP and y-EC bound closed conformation. 分子名称: ADENOSINE-5'-DIPHOSPHATE, GAMMA-GLUTAMYLCYSTEINE, Glutathione synthetase, ... 著者 Lilley, C.J, Maqbool, A, Wu, D, Yusup, H.B, Jones, L.M, Birch, P.R.J, Banfield, M.J, Urwin, P.E, Eves-van den Akker, S. 登録日 2017-07-10 公開日 2018-04-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Effector gene birth in plant parasitic nematodes: Neofunctionalization of a housekeeping glutathione synthetase gene. PLoS Genet., 14, 2018
5YEM	CATPO mutant - T188F 分子名称: CALCIUM ION, Catalase, PROTOPORPHYRIN IX CONTAINING FE 著者 Yuzugullu Karakus, Y, Balci, S, Goc, G, Pearson, A.R, Yorke, B. 登録日 2017-09-18 公開日 2018-07-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Investigation of how gate residues in the main channel affect the catalytic activity of Scytalidium thermophilum catalase. Acta Crystallogr D Struct Biol, 80, 2024
7LK1	Ornithine Aminotransferase (OAT) with its potent inhibitor - (S)-3-amino-4,4-difluorocyclopent-1-enecarboxylic acid (SS-1-148) - 1 Hour Soaking 分子名称: (1R,4R)-4-fluoro-3-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-2-ene-1-carboxylic acid, Ornithine aminotransferase, mitochondrial 著者 Butrin, A, Shen, S, Liu, D, Silverman, R. 登録日 2021-02-01 公開日 2022-02-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Turnover and Inactivation Mechanisms for ( S )-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. J.Am.Chem.Soc., 143, 2021
5IXA	HCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt 分子名称: DNA polymerase processivity factor 著者 Chen, H, Coen, D.M, Hogle, J.M, Filman, D.J. 登録日 2016-03-23 公開日 2016-11-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.684 Å) 主引用文献 A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions. ACS Infect Dis, 3, 2017
7BAS	A de novo pentameric coiled-coil assembly: CC-Type2-(TgLaId)4-W19BrPhe. 分子名称: CC-Type2-(TgLaId)4-W19BrPhe. 著者 Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. 登録日 2020-12-16 公開日 2021-04-28 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
5YIV	Caulobacter crescentus GcrA DNA-binding domain(DBD) in complex with methylated dsDNA(crystal form 1) 分子名称: Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*GP*(6MA)P*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*(6MA)P*TP*TP*CP*G)-3') 著者 Wu, X, Zhang, Y. 登録日 2017-10-06 公開日 2018-03-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.914 Å) 主引用文献 Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
5O21	Crystal structure of WNK3 kinase domain in a monophosphorylated state with chloride bound in the active site 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Serine/threonine-protein kinase WNK3 著者 Pinkas, D.M, Bufton, J.C, Kupinska, K, Wang, D, Fairhead, M, Chalk, R, Berridge, G, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2017-05-19 公開日 2017-06-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal structure of WNK3 kinase domain in a monophosphorylated state with chloride bound in the active site To Be Published
7BAU	A de novo pentameric coiled-coil assembly: CC-Type2-(TgIaId)4-W19BrPhe. 分子名称: CC-Type2-(TgLaId)4-W19BrPhe. 著者 Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. 登録日 2020-12-16 公開日 2021-04-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
7BAV	A de novo pentameric coiled-coil assembly: CC-Type2-(TgLaId)4-W19BrPhe. 分子名称: CC-Type2-(TgLaId)4-W19BrPhe 著者 Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. 登録日 2020-12-16 公開日 2021-04-28 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
7BAW	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(GgIaId)4 分子名称: CC-Type2-(GgIaId)4, GLYCEROL, N-PROPANOL 著者 Martin, F.J.O, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2020-12-16 公開日 2021-04-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
5CWB	Crystal structure of de novo designed helical repeat protein DHR4 分子名称: Designed helical repeat protein 著者 Bhabha, G, Ekiert, D.C. 登録日 2015-07-27 公開日 2015-12-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Exploring the repeat protein universe through computational protein design. Nature, 528, 2015
6UZR	Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and homoquinolinic acid 分子名称: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCEROL, GLYCINE, ... 著者 Wang, J.X, Furukawa, H. 登録日 2019-11-15 公開日 2020-01-29 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11, 2020
5CWK	Crystal structure of de novo designed helical repeat protein DHR53 分子名称: Designed helical repeat protein 著者 Bhabha, G, Ekiert, D.C. 登録日 2015-07-28 公開日 2015-12-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploring the repeat protein universe through computational protein design. Nature, 528, 2015
5HK6	Bacterial sodium channel neck 3G mutant, SAD 分子名称: Ion transport protein 著者 Rohaim, A, Minor, D.L. 登録日 2016-01-13 公開日 2016-03-09 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation. Cell, 164, 2016
5HKD	Bacterial sodium channel neck 7G mutant 分子名称: CALCIUM ION, Ion transport protein 著者 Rohaim, A, Minor, D.L. 登録日 2016-01-13 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation. Cell, 164, 2016
6V0P	PRMT5 complex bound to covalent PBM inhibitor BRD6711 分子名称: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-sulfamoylphenyl)acetamide, CHLORIDE ION, GLYCEROL, ... 著者 McMillan, B.J, McKinney, D.C. 登録日 2019-11-19 公開日 2020-11-25 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction. J.Med.Chem., 64, 2021
8HW5	Crystal structure of African swine fever virus CP312R 分子名称: ACETIC ACID, CP312R 著者 Wang, W.M, Wang, Z.Y, Fu, D, Guo, Y. 登録日 2022-12-29 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 African swine fever virus CP312R is essential for virus replication and inhibits host protein expression by interacting with RPS27A To Be Published
6Y0Z	X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126K 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. 登録日 2020-02-10 公開日 2020-02-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
2K0N	Solution Structure of Yeast Gal11p kix domain 分子名称: Mediator of RNA polymerase II transcription subunit 15 著者 Arthanari, H, Frueh, D.P, Wagner, G.K, Naar, A.M. 登録日 2008-02-04 公開日 2008-03-25 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature, 452, 2008
3T7M	Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form 分子名称: 1,2-ETHANEDIOL, Glycogenin-1, MANGANESE (II) ION, ... 著者 Chaikuad, A, Froese, D.S, Krysztofinska, E, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Oppermann, U, Yue, W.W, Structural Genomics Consortium (SGC) 登録日 2011-07-30 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis. Proc.Natl.Acad.Sci.USA, 108, 2011
4RL0	Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins 分子名称: (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase NDM-1, ZINC ION 著者 Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W. 登録日 2014-10-14 公開日 2014-11-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins. J.Am.Chem.Soc., 136, 2014

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