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5IXA

HCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt

Summary for 5IXA
Entry DOI10.2210/pdb5ixa/pdb
Related1T6L 1YYP 5IWD
DescriptorDNA polymerase processivity factor (2 entities in total)
Functional Keywordshcmv pol accessory subunit, protein-protein interaction, human cytomegalovirus, dna polymerase, processivity factor, replication
Biological sourceHuman cytomegalovirus (strain AD169) (HHV-5)
Total number of polymer chains2
Total formula weight65153.01
Authors
Chen, H.,Coen, D.M.,Hogle, J.M.,Filman, D.J. (deposition date: 2016-03-23, release date: 2016-11-30, Last modification date: 2023-09-27)
Primary citationChen, H.,Coseno, M.,Ficarro, S.B.,Mansueto, M.S.,Komazin-Meredith, G.,Boissel, S.,Filman, D.J.,Marto, J.A.,Hogle, J.M.,Coen, D.M.
A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
ACS Infect Dis, 3:112-118, 2017
Cited by
PubMed: 28183184
DOI: 10.1021/acsinfecdis.6b00079
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.684 Å)
Structure validation

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