PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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6CR5	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH2-beta, gamma dATP analogue 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl]adenosine, DNA polymerase beta, Downstream Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
7QTT	Structural organization of a late activated human spliceosome (Baqr, core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Pena, V. 登録日 2022-01-15 公開日 2023-05-10 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
6ICZ	Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
7W59	The cryo-EM structure of human pre-C*-I complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7W5B	The cryo-EM structure of human C* complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7W5A	The cryo-EM structure of human pre-C*-II complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
6ID0	Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Schmitzova, J, Pena, V. 登録日 2023-02-07 公開日 2023-05-10 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
5EG8	The cap binding site of influenza virus protein PB2 as a drug target 分子名称: Polymerase basic protein 2, THIOCYANATE ION 著者 Liu, Y, Zheng, X, Severin, C, Rocha de Moura, T, Li, K, Luo, M. 登録日 2015-10-26 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 The cap-binding site of influenza virus protein PB2 as a drug target. Acta Crystallogr D Struct Biol, 72, 2016
4KHU	Ternary complex of rb69 mutant L415F with a ribonucleotide at -1 position 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), DNA polymerase, ... 著者 Clausen, A.R, Pedersen, L.C. 登録日 2013-05-01 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KHW	Ternary complex of RB69 mutant L415F with ribonucleotide at -2 position 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), DNA polymerase, ... 著者 Clausen, A.R, Pedersen, L.C. 登録日 2013-05-01 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.371 Å) 主引用文献 Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KI6	Ternary complex of rb69 mutant l415f with ribonucleotides at -1 and -2 position 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), DNA polymerase, ... 著者 Clausen, A.R, Pedersen, L.C. 登録日 2013-05-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KHY	Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), DNA polymerase, ... 著者 Clausen, A.R, Pedersen, L.C. 登録日 2013-05-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KI4	Ternary complex of rb69 mutant L415F with ribonucleotides at 0 and -1 position 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), DNA polymerase, ... 著者 Clausen, A.R, Pedersen, L.C. 登録日 2013-05-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
4KHS	Ternary complex of RB69 mutant L415F with a ribonucleotide at 0 position 分子名称: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*C)-3'), ... 著者 Clausen, A.R, Pedersen, L.C. 登録日 2013-05-01 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc.Natl.Acad.Sci.USA, 110, 2013
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
1NBS	Crystal structure of the specificity domain of Ribonuclease P RNA 分子名称: LEAD (II) ION, MAGNESIUM ION, RIBONUCLEASE P RNA 著者 Krasilnikov, A.S, Yang, X, Pan, T, Mondragon, A. 登録日 2002-12-03 公開日 2003-02-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Crystal structure of the specificity domain of Ribonuclease P Nature, 421, 2003
8Q7W	Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-17 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7X	Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-17 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7Q	Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-16 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
8Q7V	Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Riabov Bassat, D, Plaschka, C, Vorlaender, M.K. 登録日 2023-08-17 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of human U5 snRNP late biogenesis and recycling. Nat.Struct.Mol.Biol., 31, 2024
6GP9	Structural studies of hepatitis C virus non-structural protein-5b of genotype 4a 分子名称: RNA-directed RNA polymerase 著者 Janowski, R, Geber, H, Protzer, U, Niessing, D. 登録日 2018-06-05 公開日 2020-09-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural studies of hepatitis C virus non-structural protein-5b of genotype 4a Biorxiv, 2022
1NVP	HUMAN TFIIA/TBP/DNA COMPLEX 分子名称: 5'-D(*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*G)-3', TATA box binding protein, ... 著者 Bleichenbacher, M, Tan, S, Richmond, T.J. 登録日 2003-02-04 公開日 2003-10-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes. J.Mol.Biol., 332, 2003
7AQO	yeast THO-Sub2 complex dimer 分子名称: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... 著者 Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. 登録日 2020-10-22 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
1NH2	Crystal structure of a yeast TFIIA/TBP/DNA complex 分子名称: 5'-D(*GP*TP*TP*TP*TP*AP*TP*AP*TP*AP*CP*AP*TP*AP*CP*A)-3', 5'-D(*TP*GP*TP*AP*(5IU)P*GP*TP*AP*TP*AP*(5IU)P*AP*AP*AP*AP*C)-3', Transcription initiation factor IIA large chain, ... 著者 Bleichenbacher, M, Tan, S, Richmond, T.J. 登録日 2002-12-18 公開日 2003-10-21 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes. J.Mol.Biol., 332, 2003

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