PDB: 1342 件ウェブページステータス検索Chemie searchBIRD

---

4HAU	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAY	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB3	Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB4	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAZ	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAW	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAX	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB0	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAV	Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 分子名称: Anguinomycin A, bound form, CHLORIDE ION, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HLQ	Crystal structure of human rab1b bound to GDP and BEF3 in complex with the GAP domain of TBC1D20 from homo sapiens 分子名称: BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Gazdag, E.M, Gavriljuk, K, Itzen, A, Koetting, C, Gerwert, K, Goody, R.S. 登録日 2012-10-17 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail. Proc.Natl.Acad.Sci.USA, 109, 2012
4I1O	Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3 分子名称: BERYLLIUM TRIFLUORIDE ION, DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Gazdag, E.M, Streller, A, Vetter, I.R, Goody, R.S, Itzen, A. 登録日 2012-11-21 公開日 2013-01-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. Embo Rep., 14, 2013
4ITR	Crystal Structure of IbpAFic2-H3717A in complex with adenylylated Cdc42 分子名称: ADENOSINE MONOPHOSPHATE, Adenosine monophosphate-protein transferase and cysteine protease IbpA, Cell division control protein 42 homolog, ... 著者 Xiao, J, Dixon, J.E. 登録日 2013-01-18 公開日 2013-02-20 最終更新日 2023-06-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of Fic-mediated adenylylation. Nat.Struct.Mol.Biol., 17, 2010
4G01	ARA7-GDP-Ca2+/VPS9a 分子名称: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein RABF2b, ... 著者 Ihara, K. 登録日 2012-07-09 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Direct metal recognition by guanine nucleotide-exchange factor in the initial step of the exchange reaction Acta Crystallogr.,Sect.D, 69, 2013
3W3Z	Crystal structure of Kap121p bound to RanGTP 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-3, ... 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2014-01-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
3ZJY	Crystal Structure of Importin 13 - RanGTP - eIF1A complex 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL, GTP-BINDING NUCLEAR PROTEIN RAN, ... 著者 Gruenwald, M, Lazzaretti, D, Bono, F. 登録日 2013-01-21 公開日 2013-04-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural Basis for the Nuclear Export Activity of Importin13. Embo J., 32, 2013
4JVS	Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3 分子名称: ACETIC ACID, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Yu, Q, Yao, Q, Wang, D.-C, Shao, F. 登録日 2013-03-26 公開日 2013-05-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.783 Å) 主引用文献 Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP Cell Res., 23, 2013
2LWI	Solution structure of H-RasT35S mutant protein in complex with Kobe2601 分子名称: 2-(2,4-dinitrophenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide, GTPase HRas, MAGNESIUM ION, ... 著者 Araki, M, Tamura, A, Shima, F, Kataoka, T. 登録日 2012-08-01 公開日 2013-05-22 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc.Natl.Acad.Sci.USA, 110, 2013
4HDQ	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail 分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ... 著者 Gingras, A.R. 登録日 2012-10-02 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail. J.Biol.Chem., 288, 2013
4IRU	Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3 分子名称: ACETATE ION, ALUMINUM FLUORIDE, GLYCEROL, ... 著者 Mishra, A.K, Delcampo, C.M, Collins, R.E, Roy, C.R, Lambright, D.G. 登録日 2013-01-15 公開日 2013-07-10 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism. J.Biol.Chem., 288, 2013
4HDO	Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase 分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ... 著者 Gingras, A.R. 登録日 2012-10-02 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail. J.Biol.Chem., 288, 2013
4G0N	Crystal Structure of wt H-Ras-GppNHp bound to the RBD of Raf Kinase 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, ACETATE ION, CALCIUM ION, ... 著者 Fetics, S.K, Kearney, B.M, Buhrman, G, Mattos, C. 登録日 2012-07-09 公開日 2013-07-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD. Structure, 23, 2015
4G3X	Crystal Structure of Q61L H-Ras-GppNHp bound to the RBD of Raf Kinase 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Fetics, S.K, Kearney, B.M, Buhrman, G, Mattos, C. 登録日 2012-07-15 公開日 2013-07-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD. Structure, 23, 2015
4K81	Crystal structure of the Grb14 RA and PH domains in complex with GTP-loaded H-Ras 分子名称: GLYCEROL, GTPase HRas, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Qamra, R, Hubbard, S.R. 登録日 2013-04-17 公開日 2013-09-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the interaction of the adaptor protein grb14 with activated ras. Plos One, 8, 2013
4C4P	Crystal Structure of Wild-Type Rab11 Complexed to FIP2 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB11 FAMILY-INTERACTING PROTEIN 2, ... 著者 Sultana, A, Khan, A.R. 登録日 2013-09-07 公開日 2013-09-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Functional Analysis of Fip2 Binding to the Endosome-Localised Rab25 Gtpase Biochim.Biophys.Acta, 1834, 2013

<12131415161718192021222324252627>