2AUG
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![BU of 2aug by Molmil](/molmil-images/mine/2aug) | Crystal structure of the Grb14 SH2 domain | 分子名称: | Growth factor receptor-bound protein 14 | 著者 | Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. | 登録日 | 2005-08-27 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20, 2005
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2AOB
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![BU of 2aob by Molmil](/molmil-images/mine/2aob) | Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | 登録日 | 2005-08-12 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
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2AOA
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![BU of 2aoa by Molmil](/molmil-images/mine/2aoa) | Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Growth factor receptor-bound protein 2 | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | 登録日 | 2005-08-12 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
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2ABL
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![BU of 2abl by Molmil](/molmil-images/mine/2abl) | |
1ZFP
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![BU of 1zfp by Molmil](/molmil-images/mine/1zfp) | |
1Z3K
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![BU of 1z3k by Molmil](/molmil-images/mine/1z3k) | |
1YVL
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![BU of 1yvl by Molmil](/molmil-images/mine/1yvl) | Structure of Unphosphorylated STAT1 | 分子名称: | 5-residue peptide, GOLD ION, Signal transducer and activator of transcription 1-alpha/beta | 著者 | Mao, X, Ren, Z, Parker, G.N, Sondermann, H, Pastorello, M.A, Wang, W, McMurray, J.S, Demeler, B, Darnell Jr, J.E, Chen, X. | 登録日 | 2005-02-16 | 公開日 | 2005-03-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural bases of unphosphorylated STAT1 association and receptor binding. Mol.Cell, 17, 2005
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1Y57
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![BU of 1y57 by Molmil](/molmil-images/mine/1y57) | Structure of unphosphorylated c-Src in complex with an inhibitor | 分子名称: | 4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]PHENYL}BENZAMIDE, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION | 著者 | Cowan-Jacob, S.W, Fendrich, G, Manley, P.W, Jahnke, W, Fabbro, D, Liebetanz, J, Meyer, T. | 登録日 | 2004-12-02 | 公開日 | 2005-06-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | The Crystal Structure of a c-Src Complex in an Active Conformation Suggests Possible Steps in c-Src Activation Structure, 13, 2005
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1Y1U
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![BU of 1y1u by Molmil](/molmil-images/mine/1y1u) | Structure of unphosphorylated STAT5a | 分子名称: | Signal transducer and activator of transcription 5A | 著者 | Neculai, D, Neculai, A.M, Verrier, S, Straub, K, Klumpp, K, Pfitzner, E, Becker, S. | 登録日 | 2004-11-19 | 公開日 | 2005-10-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Structure of the unphosphorylated STAT5a dimer J.Biol.Chem., 280, 2005
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1XA6
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![BU of 1xa6 by Molmil](/molmil-images/mine/1xa6) | Crystal Structure of the Human Beta2-Chimaerin | 分子名称: | Beta2-chimaerin, ZINC ION | 著者 | Canagarajah, B, Leskow, F.C, Ho, J.Y, Mischak, H, Saidi, L.F, Kazanietz, M.G, Hurley, J.H. | 登録日 | 2004-08-25 | 公開日 | 2004-11-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin. Cell(Cambridge,Mass.), 119, 2004
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1X6C
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![BU of 1x6c by Molmil](/molmil-images/mine/1x6c) | Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 | 分子名称: | Tyrosine-protein phosphatase, non-receptor type 6 | 著者 | Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-17 | 公開日 | 2005-11-17 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 To be Published
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1X27
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![BU of 1x27 by Molmil](/molmil-images/mine/1x27) | Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas | 分子名称: | CRK-associated substrate, Proto-oncogene tyrosine-protein kinase LCK, SODIUM ION | 著者 | Nasertorabi, F, Tars, K, Becherer, K, Kodandapani, R, Liljas, L, Vuori, K, Ely, K.R. | 登録日 | 2005-04-20 | 公開日 | 2006-02-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis for regulation of Src by the docking protein p130Cas J.MOL.RECOG., 19, 2006
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1X0N
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![BU of 1x0n by Molmil](/molmil-images/mine/1x0n) | NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor | 分子名称: | 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID, Growth factor receptor-bound protein 2 | 著者 | Ogura, K, Shiga, T, Yuzawa, S, Yokochi, M, Burke, T.R, Inagaki, F. | 登録日 | 2005-03-24 | 公開日 | 2005-04-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor To be Published
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1WQU
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![BU of 1wqu by Molmil](/molmil-images/mine/1wqu) | Solution structure of the human FES SH2 domain | 分子名称: | Proto-oncogene tyrosine-protein kinase FES/FPS | 著者 | Scott, A, Pantoja-Uceda, D, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Tanaka, A, Sugano, S, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-10-02 | 公開日 | 2005-06-14 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes J.Biomol.NMR, 31, 2005
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1UUS
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![BU of 1uus by Molmil](/molmil-images/mine/1uus) | Structure of an activated Dictyostelium STAT in its DNA-unbound form | 分子名称: | STAT PROTEIN | 著者 | Soler-Lopez, M, Petosa, C, Fukuzawa, M, Ravelli, R, Williams, J.G, Muller, C.W. | 登録日 | 2004-01-09 | 公開日 | 2004-03-26 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of an Activated Dictyostelium Stat in its DNA-Unbound Form Mol.Cell, 13, 2004
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1UUR
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![BU of 1uur by Molmil](/molmil-images/mine/1uur) | Structure of an activated Dictyostelium STAT in its DNA-unbound form | 分子名称: | STATA PROTEIN | 著者 | Soler-Lopez, M, Petosa, C, Fukuzawa, M, Ravelli, R, Williams, J.G, Muller, C.W. | 登録日 | 2004-01-09 | 公開日 | 2004-03-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of an Activated Dictyostelium Stat in its DNA-Unbound Form Mol.Cell, 13, 2004
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1TZE
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![BU of 1tze by Molmil](/molmil-images/mine/1tze) | |
1TCE
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![BU of 1tce by Molmil](/molmil-images/mine/1tce) | SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR, SHC | 著者 | Zhou, M.-M, Meadows, R.P, Logan, T.M, Yoon, H.S, Wade, W.R, Ravichandran, K.S, Burakoff, S.J, Feisk, S.W. | 登録日 | 1996-03-27 | 公開日 | 1997-05-15 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor. Proc.Natl.Acad.Sci.USA, 92, 1995
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1SPS
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![BU of 1sps by Molmil](/molmil-images/mine/1sps) | |
1SPR
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![BU of 1spr by Molmil](/molmil-images/mine/1spr) | |
1SKJ
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![BU of 1skj by Molmil](/molmil-images/mine/1skj) | COCRYSTAL STRUCTURE OF UREA-SUBSTITUTED PHOSPHOPEPTIDE COMPLEX | 分子名称: | 4-[3-CARBOXYMETHYL-3-(4-PHOSPHONOOXY-BENZYL)-UREIDO]-4-[(3-CYCLOHEXYL-PROPYL)-METHYL-CARBAMOYL]BUTYRIC ACID, PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN | 著者 | Holland, D.R, Rubin, J.R. | 登録日 | 1997-09-18 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand. J.Med.Chem., 40, 1997
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1SHD
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![BU of 1shd by Molmil](/molmil-images/mine/1shd) | |
1SHB
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![BU of 1shb by Molmil](/molmil-images/mine/1shb) | |
1SHA
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![BU of 1sha by Molmil](/molmil-images/mine/1sha) | |
1RQQ
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![BU of 1rqq by Molmil](/molmil-images/mine/1rqq) | Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS | 分子名称: | BISUBSTRATE INHIBITOR, Insulin receptor, MANGANESE (II) ION, ... | 著者 | Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R. | 登録日 | 2003-12-06 | 公開日 | 2003-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol.Cell, 12, 2003
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