2AUG

Crystal structure of the Grb14 SH2 domain

Summary for 2AUG

Entry DOI	10.2210/pdb2aug/pdb
Descriptor	Growth factor receptor-bound protein 14 (2 entities in total)
Functional Keywords	phosphorylation, sh2 domain, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q14449
Total number of polymer chains	2
Total formula weight	29267.42
Authors	Depetris, R.S.,Hu, J.,Gimpelevich, I.,Holt, L.J.,Daly, R.J.,Hubbard, S.R. (deposition date: 2005-08-27, release date: 2005-11-01, Last modification date: 2023-08-23)
Primary citation	Depetris, R.S.,Hu, J.,Gimpelevich, I.,Holt, L.J.,Daly, R.J.,Hubbard, S.R. Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20:325-333, 2005 Cited by PubMed: 16246733 DOI: 10.1016/j.molcel.2005.09.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation