2AUG
Crystal structure of the Grb14 SH2 domain
Summary for 2AUG
Entry DOI | 10.2210/pdb2aug/pdb |
Descriptor | Growth factor receptor-bound protein 14 (2 entities in total) |
Functional Keywords | phosphorylation, sh2 domain, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q14449 |
Total number of polymer chains | 2 |
Total formula weight | 29267.42 |
Authors | Depetris, R.S.,Hu, J.,Gimpelevich, I.,Holt, L.J.,Daly, R.J.,Hubbard, S.R. (deposition date: 2005-08-27, release date: 2005-11-01, Last modification date: 2023-08-23) |
Primary citation | Depetris, R.S.,Hu, J.,Gimpelevich, I.,Holt, L.J.,Daly, R.J.,Hubbard, S.R. Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20:325-333, 2005 Cited by PubMed: 16246733DOI: 10.1016/j.molcel.2005.09.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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