2AUG

Crystal structure of the Grb14 SH2 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Growth factor receptor-bound protein 14	polymer	126	14633.7	2	UniProt (Q14449) Pfam (PF00017)	Homo sapiens (human)	GRB14 adaptor protein
2	C, D (A, B)	water	water		18.0	156	Chemie (HOH)

Sequence modifications

A, B: 433 - 537 (UniProt: Q14449)

PDB	External Database	Details
Met 412	-	expression tag
Gly 413	-	expression tag
Ser 414	-	expression tag
Ser 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
Ser 422	-	expression tag
Ser 423	-	expression tag
Gly 424	-	expression tag
Leu 425	-	expression tag
Val 426	-	expression tag
Pro 427	-	expression tag
Arg 428	-	expression tag
Gly 429	-	expression tag
Ser 430	-	expression tag
His 431	-	expression tag
Met 432	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29267.4
All*	Total formula weight	29267.4

*Water molecules are not included.