PDB: 682 件ウェブページステータス検索Chemie searchBIRD

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6P8V	Structure of E. coli MS115-1 HORMA:CdnC:Trip13 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATPase, AAA family, ... 著者 Ye, Q, Corbett, K.D. 登録日 2019-06-08 公開日 2019-12-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
6P07	Spastin hexamer in complex with substrate 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Sandate, C.R, Szyk, A, Zehr, E, Roll-Mecak, A, Lander, G.C. 登録日 2019-05-16 公開日 2019-06-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 An allosteric network in spastin couples multiple activities required for microtubule severing. Nat.Struct.Mol.Biol., 26, 2019
6P14	Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form B) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, ACETATE ION, ... 著者 Pisa, R, Cupido, T, Kapoor, T.M. 登録日 2019-05-17 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93001127 Å) 主引用文献 Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
6PDY	Msp1-substrate complex in open conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Wang, L, Myasnikov, A, Pan, X, Walter, P. 登録日 2019-06-19 公開日 2020-02-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife, 9, 2020
6P13	Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form A) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, SULFATE ION, ... 著者 Pisa, R, Cupido, T, Kapoor, T.M. 登録日 2019-05-17 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
6PEK	Structure of Spastin Hexamer (Subunit A-E) in complex with substrate peptide 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P. 登録日 2019-06-20 公開日 2019-12-04 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. J.Biol.Chem., 295, 2020
6PDW	Msp1-substrate complex in closed conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Wang, L, Myasnikov, A, Pan, X, Walter, P. 登録日 2019-06-19 公開日 2020-02-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife, 9, 2020
6PEN	Structure of Spastin Hexamer (whole model) in complex with substrate peptide 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, EYEYEYEYEY, ... 著者 Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P. 登録日 2019-06-20 公開日 2019-12-04 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. J.Biol.Chem., 295, 2020
6PXI	The crystal structure of a singly capped HslUV complex with an axial pore plug and a HslU E257Q mutation 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... 著者 Baytshtok, V, Grant, R.A, Sauer, R.T. 登録日 2019-07-26 公開日 2020-07-29 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (3.447 Å) 主引用文献 Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
6E10	PTEX Core Complex in the Engaged (Extended) State 分子名称: Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... 著者 Ho, C, Lai, M, Zhou, Z.H. 登録日 2018-07-08 公開日 2018-08-22 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (4.16 Å) 主引用文献 Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
7QXX	Proteasome-ZFAND5 Complex Z+E state 分子名称: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-27 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXN	Proteasome-ZFAND5 Complex Z+A state 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-26 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QY7	Proteasome-ZFAND5 Complex Z-A state 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-27 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QYB	Proteasome-ZFAND5 Complex Z-C state 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-27 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXP	Proteasome-ZFAND5 Complex Z+B state 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-26 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXU	Proteasome-ZFAND5 Complex Z+C state 分子名称: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-27 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXW	Proteasome-ZFAND5 Complex Z+D state 分子名称: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-27 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QYA	Proteasome-ZFAND5 Complex Z-B state 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhu, Y, Lu, Y. 登録日 2022-01-27 公開日 2023-02-08 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7R7S	p47-bound p97-R155H mutant with ATPgammaS 分子名称: NSFL1 cofactor p47, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. 登録日 2021-06-25 公開日 2021-08-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
7R7T	p47-bound p97-R155H mutant with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, NSFL1 cofactor p47, Transitional endoplasmic reticulum ATPase 著者 Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. 登録日 2021-06-25 公開日 2021-08-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
6EF2	Yeast 26S proteasome bound to ubiquitinated substrate (5T motor state) 分子名称: 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... 著者 de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. 登録日 2018-08-15 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.27 Å) 主引用文献 Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
7R7U	D1 and D2 domain structure of the p97(R155H)-p47 complex 分子名称: Transitional endoplasmic reticulum ATPase 著者 Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. 登録日 2021-06-25 公開日 2021-08-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
6EM9	S.aureus ClpC resting state, asymmetric map 分子名称: ATP-dependent Clp protease ATP-binding subunit ClpC 著者 Carroni, M, Mogk, A, Bukau, B, Franke, K. 登録日 2017-10-01 公開日 2017-12-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
7RLH	Cryo-EM structure of human p97-D592N mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLG	Cryo-EM structure of human p97-D592N mutant bound to ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021

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