6PEN

Structure of Spastin Hexamer (whole model) in complex with substrate peptide

Summary for 6PEN

• Entry DOI: 10.2210/pdb6pen/pdb
• Related: 6PEK
• EMDB information: 20327
• Descriptor: Spastin, EYEYEYEYEY, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: aaa+ atpase, microtubule severing, motor protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 7
• Total formula weight: 330966.67

Authors

Han, H.,Schubert, H.L.,McCullough, J.,Monroe, N.,Sundquist, W.I.,Hill, C.P. (deposition date: 2019-06-20, release date: 2019-12-04, Last modification date: 2024-03-13)

• Primary citation: Han, H.,Schubert, H.L.,McCullough, J.,Monroe, N.,Purdy, M.D.,Yeager, M.,Sundquist, W.I.,Hill, C.P.; Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.; J.Biol.Chem., 295:435-443, 2020; PubMed: 31767681; DOI: 10.1074/jbc.AC119.009890

Experimental method

ELECTRON MICROSCOPY (4.2 Å)