PDB: 7770 件ウェブページステータス検索Chemie searchBIRD

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1WAW	Specificity and affinity of natural product cyclopentapeptide inhibitor Argadin against human chitinase 分子名称: ARGADIN, CHITOTRIOSIDASE 1, GLYCEROL, ... 著者 Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F. 登録日 2004-10-28 公開日 2005-01-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12, 2005
1JQG	Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera 分子名称: ZINC ION, carboxypeptidase A 著者 Estebanez-Perpina, E, Bayes, A, Vendrell, J, Jongsma, M.A, Bown, D.P, Gatehouse, J.A, Huber, R, Bode, W, Aviles, F.X, Reverter, D. 登録日 2001-08-07 公開日 2002-08-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera. J.Mol.Biol., 313, 2001
1W50	Apo Structure of BACE (Beta Secretase) 分子名称: BETA-SECRETASE 1, IODIDE ION 著者 Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J. 登録日 2004-08-04 公開日 2004-09-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Apo and Inhibitor Complex Structures of Bace (Beta-Secretase) J.Mol.Biol., 343, 2004
1W51	BACE (Beta Secretase) in complex with a nanomolar non-peptidic inhibitor 分子名称: 3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)(HYDROXY)METHYL]-N,N-DIPROPYLBENZAMIDE, BETA-SECRETASE 1, IODIDE ION 著者 Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J. 登録日 2004-08-04 公開日 2004-09-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Apo and Inhibitor Complex Structures of Bace (Beta-Secretase) J.Mol.Biol., 343, 2004
1PFX	PORCINE FACTOR IXA 分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, FACTOR IXA 著者 Brandstetter, H, Bauer, M, Huber, R, Lollar, P, Bode, W. 登録日 1995-07-19 公開日 1996-08-17 最終更新日 2013-02-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. Proc.Natl.Acad.Sci.USA, 92, 1995
4GGK	Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate 分子名称: Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION 著者 Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L. 登録日 2012-08-06 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature, 491, 2012
1YU6	Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex 分子名称: CALCIUM ION, Ovomucoid, Subtilisin Carlsberg 著者 Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G. 登録日 2005-02-11 公開日 2005-05-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations. Acta Crystallogr.,Sect.D, 61, 2005
1PJU	Unbound form of Tomato Inhibitor-II 分子名称: SULFATE ION, Wound-induced proteinase inhibitor II 著者 Barrette-Ng, I.H, Ng, K.K.-S, Cherney, M.M, Pearce, G, Ghani, U, Ryan, C.A, James, M.N.G. 登録日 2003-06-03 公開日 2003-09-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Unbound form of tomato inhibitor-II reveals interdomain flexibility and conformational variability in the reactive site loops J.Biol.Chem., 278, 2003
4GL0	Putative spermidine/putrescine ABC transporter from Listeria monocytogenes 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Lmo0810 protein, ... 著者 Osipiuk, J, Zhou, M, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-08-13 公開日 2012-08-22 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Putative spermidine/putrescine ABC transporter from Listeria monocytogenes To be Published
1KTL	The human non-classical major histocompatibility complex molecule HLA-E 分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... 著者 Holmes, M.A, Strong, R.K. 登録日 2002-01-16 公開日 2003-02-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities J.Biol.Chem., 278, 2003
1PK6	Globular Head of the Complement System Protein C1q 分子名称: CALCIUM ION, Complement C1q subcomponent, A chain precursor, ... 著者 Gaboriaud, C, Juanhuix, J, Gruez, A, Lacroix, M, Darnault, C, Pignol, D, Verger, D, Fontecilla-Camps, J.C, Arlaud, G.J. 登録日 2003-06-05 公開日 2003-10-21 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J.Biol.Chem., 278, 2003
4GLY	Human urokinase-type plasminogen activator uPA in complex with the two-disulfide bridge peptide UK504 分子名称: BICYCLIC PEPTIDE INHIBITOR UK504, CHLORIDE ION, GLYCEROL, ... 著者 Buth, S.A, Leiman, P.G, Chen, S, Heinis, C. 登録日 2012-08-15 公開日 2013-05-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.518 Å) 主引用文献 Bicyclic Peptide Ligands Pulled out of Cysteine-Rich Peptide Libraries. J.Am.Chem.Soc., 135, 2013
1I34	SOLUTION DNA QUADRUPLEX WITH DOUBLE CHAIN REVERSAL LOOP AND TWO DIAGONAL LOOPS CONNECTING GGGG TETRADS FLANKED BY G-(T-T) TRIAD AND T-T-T TRIPLE 分子名称: 5'-D(*GP*GP*TP*TP*TP*TP*GP*GP*CP*AP*GP*GP*GP*TP*TP*TP*TP*GP*GP*T)-3' 著者 Kuryavyi, V, Majumdar, A, Shallop, A, Chernichenko, N, Skripkin, E, Jones, R, Patel, D.J. 登録日 2001-02-12 公開日 2001-06-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple. J.Mol.Biol., 310, 2001
8U5L	MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK virus VP1 分子名称: Capsid protein VP1, scFv fragment of the monoclonal antibody MAU868 著者 Knapp, M.S, Ornelas, E. 登録日 2023-09-12 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Nonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1. Am J Transplant, 2024
4FBN	Insights into structural integration of the PLCgamma regulatory region and mechanism of autoinhibition and activation based on key roles of SH2 domains 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 著者 Cole, A.R, Mas-Droux, C.P, Bunney, T.D, Katan, M. 登録日 2012-05-23 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation. Structure, 20, 2012
4FIN	Crystal Structure of EttA (formerly YjjK) - an E. coli ABC-type ATPase 分子名称: CITRIC ACID, EttA (YjjK) ABCF family protein, GLYCEROL, ... 著者 Smith, P, Yuan, Y, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2012-06-09 公開日 2013-07-03 最終更新日 2014-03-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The ABC-F protein EttA gates ribosome entry into the translation elongation cycle. Nat.Struct.Mol.Biol., 21, 2014
1N4F	Para-Arsanilate Derivative of Hen Egg-White Lysozyme 分子名称: 1,2-ETHANEDIOL, 4-AMINOPHENYLARSONIC ACID, Lysozyme C, ... 著者 Retailleau, P, Prange, T. 登録日 2002-10-31 公開日 2003-05-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Phasing power at the K absorption edge of organic arsenic. Acta Crystallogr.,Sect.D, 59, 2003
4FOC	Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 2 分子名称: ALK tyrosine kinase receptor, methyl cis-4-[2-(benzoylamino)-6-(piperidin-1-ylmethyl)-1H-benzimidazol-1-yl]cyclohexanecarboxylate 著者 Whittington, D.A, Epstein, L.F, Chen, H. 登録日 2012-06-20 公開日 2012-07-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer. J.Med.Chem., 55, 2012
1KLT	CRYSTAL STRUCTURE OF PMSF-TREATED HUMAN CHYMASE AT 1.9 ANGSTROMS RESOLUTION 分子名称: CHYMASE, phenylmethanesulfonic acid 著者 Mcgrath, M.E. 登録日 1997-10-16 公開日 1998-12-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A. Biochemistry, 36, 1997
1YJA	SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 20% DIMETHYLFORMAMIDE 分子名称: CALCIUM ION, SUBTILISIN 8397+1 著者 Kidd, R.D, Farber, G.K. 登録日 1996-01-16 公開日 1996-07-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Breaking the low barrier hydrogen bond in a serine protease. Protein Sci., 8, 1999
1YJC	SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 50% DIMETHYLFORMAMIDE 分子名称: CALCIUM ION, SUBTILISIN 8397+1 著者 Kidd, R.D, Farber, G.K. 登録日 1996-01-16 公開日 1996-07-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Breaking the low barrier hydrogen bond in a serine protease. Protein Sci., 8, 1999
4H1S	Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, PHOSPHATE ION, ... 著者 Heuts, D.P, Weissenborn, M.J, Olkhov, R.V, Shaw, A.M, Levy, C.W, Scrutton, N.S. 登録日 2012-09-11 公開日 2012-10-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity. Chembiochem, 13, 2012
1KBQ	Complex of Human NAD(P)H quinone Oxidoreductase with 5-methoxy-1,2-dimethyl-3-(4-nitrophenoxymethyl)indole-4,7-dione (ES936) 分子名称: 5-METHOXY-1,2-DIMETHYL-3-(4-NITROPHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 著者 Faig, M, Bianchet, M.A, Amzel, L.M. 登録日 2001-11-06 公開日 2002-01-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches. Biochemistry, 40, 2001
1OG2	Structure of human cytochrome P450 CYP2C9 分子名称: CYTOCHROME P450 2C9, HEME C 著者 Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. 登録日 2003-04-23 公開日 2003-07-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003
1OGS	human acid-beta-glucosidase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... 著者 Dvir, H, Harel, M, McCarthy, A.A, Toker, L, Silman, I, Futerman, A.H, Sussman, J.L. 登録日 2003-05-13 公開日 2003-07-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease Embo Rep., 4, 2003

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