4H1S

Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity

Summary for 4H1S

• Entry DOI: 10.2210/pdb4h1s/pdb
• Descriptor: 5'-nucleotidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total)
• Functional Keywords: 5'-nucleotidase, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor: P21589
• Total number of polymer chains: 2
• Total formula weight: 118982.43

Authors

Heuts, D.P.,Weissenborn, M.J.,Olkhov, R.V.,Shaw, A.M.,Levy, C.W.,Scrutton, N.S. (deposition date: 2012-09-11, release date: 2012-10-03, Last modification date: 2020-07-29)

• Primary citation: Heuts, D.P.,Weissenborn, M.J.,Olkhov, R.V.,Shaw, A.M.,Gummadova, J.,Levy, C.,Scrutton, N.S.; Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity.; Chembiochem, 13:2384-2391, 2012; PubMed: 22997138; DOI: 10.1002/cbic.201200426

Experimental method

X-RAY DIFFRACTION (2.2 Å)