4H1S
Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5'-nucleotidase | polymer | 530 | 59044.2 | 2 | UniProt (P21589) Pfam (PF00149) Pfam (PF02872) | Homo sapiens (human) | 5'-NT, Ecto-5'-nucleotidase |
| 2 | C, G (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, E, H, I (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | F, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 577 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 549 (UniProt: P21589)
| PDB | External Database | Details |
|---|---|---|
| Met 26 | - | initiating methionine |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118088.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 894.0 | |
| All* | Total formula weight | 118982.4 |
