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2OB7
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Structure of tmRNA-(SmpB)2 complex as inferred from cryo-EM
分子名称: 16S ribosomal RNA, SsrA-binding protein, transfer-messenger RNA
著者Frank, J, Felden, B, Gillet, R, Li, W.
登録日2006-12-18
公開日2007-01-23
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (13.6 Å)
主引用文献Scaffolding as an organizing principle in trans-translation. The roles of small protein B and ribosomal protein S1.
J.Biol.Chem., 282, 2007
2OB9
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Structure of bacteriophage HK97 tail assembly chaperone
分子名称: Tail assembly chaperone
著者McGrath, T.E, Tuite, A, Bona, D, Saridakis, V, Edwards, A.M, Maxwell, K, Chirgadze, N.Y.
登録日2006-12-18
公開日2007-12-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A conserved spiral structure for highly diverged phage tail assembly chaperones.
J.Mol.Biol., 425, 2013
2OBA
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Pseudomonas aeruginosa 6-pyruvoyl tetrahydrobiopterin synthase
分子名称: Probable 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION
著者McGrath, T.E, Kisselman, G, Battaile, K, Romanov, V, Wu-Brown, J, Guthrie, J, Virag, C, Mansoury, K, Edwards, A.M, Pai, E.F, Chirgadze, N.Y.
登録日2006-12-18
公開日2007-01-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Pseudomonas aeruginosa 6-pyruvoyl tetrahydrobiopterin synthase
TO BE PUBLISHED
2OBB
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Structure of the conserved protein coded by locus BT_0820 from Bacteroides thetaiotaomicron
分子名称: Hypothetical protein, MAGNESIUM ION
著者Cuff, M.E, Bigelow, L, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-12-18
公開日2007-01-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the conserved protein coded by locus BT_0820 from Bacteroides thetaiotaomicron
To be Published
2OBC
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The crystal structure of RibD from Escherichia coli in complex with a substrate analogue, ribose 5-phosphate (beta form), bound to the active site of the reductase domain
分子名称: 5-O-phosphono-beta-D-ribofuranose, Riboflavin biosynthesis protein ribD
著者Moche, M, Stenmark, P, Gurmu, D, Nordlund, P, Structural Proteomics in Europe (SPINE)
登録日2006-12-18
公開日2007-02-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of the bifunctional deaminase/reductase RibD of the riboflavin biosynthetic pathway in Escherichia coli: implications for the reductive mechanism.
J.Mol.Biol., 373, 2007
2OBD
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Crystal Structure of Cholesteryl Ester Transfer Protein
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Qiu, X.
登録日2006-12-18
公開日2007-01-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.
Nat.Struct.Mol.Biol., 14, 2007
2OBE
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Crystal Structure of Chimpanzee Adenovirus (Type 68/Simian 25) Major Coat Protein Hexon
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DIHYDROGENPHOSPHATE ION, Hexon protein
著者Xue, F, Rux, J.J, Burnett, R.M.
登録日2006-12-18
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based identification of a major neutralizing site in an adenovirus hexon
J.Virol., 81, 2007
2OBF
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Structure of K57A hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy (SAH)
分子名称: (3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Drinkwater, N, Martin, J.L.
登録日2006-12-19
公開日2007-10-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase
J.Med.Chem., 50, 2007
2OBG
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Crystal Structure of Monobody MBP-74/Maltose Binding Protein Fusion Complex
分子名称: Maltose Binding periplasmic Protein and Monobody MBP-74 Fusion protein
著者Gilbreth, R.N, Tereshko, V, Koide, S.
登録日2006-12-19
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献High-affinity single-domain binding proteins with a binary-code interface.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OBH
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Centrin-XPC peptide
分子名称: CALCIUM ION, Centrin-2, DNA-repair protein complementing XP-C cells
著者Charbonnier, J.B.
登録日2006-12-19
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural, thermodynamic, and cellular characterization of human centrin 2 interaction with xeroderma pigmentosum group C protein.
J.Mol.Biol., 373, 2007
2OBI
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Crystal structure of the Selenocysteine to Cysteine Mutant of human phospholipid hydroperoxide glutathione peroxidase (GPx4)
分子名称: Phospholipid hydroperoxide glutathione peroxidase (GPX4)
著者Scheerer, P, Krauss, N, Hoehne, W.
登録日2006-12-19
公開日2007-09-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4).
Biochemistry, 46, 2007
2OBJ
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Crystal structure of human PIM-1 Kinase in complex with inhibitor
分子名称: 6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Yao, N, Cheney, I.W, Yan, S.
登録日2006-12-19
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.
Bioorg.Med.Chem.Lett., 17, 2007
2OBK
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X-Ray structure of the putative Se binding protein from Pseudomonas fluorescens. Northeast Structural Genomics Consortium target PlR6.
分子名称: SelT/selW/selH selenoprotein domain
著者Kuzin, A.P, Su, M, Seetharaman, J, Chen, C.X, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-19
公開日2007-01-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-Ray structure of the putative Se binding protein from Pseudomonas fluorescens
To be Published
2OBL
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Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria
分子名称: ACETATE ION, CALCIUM ION, EscN, ...
著者Zarivach, R, Vuckovic, M, Deng, W, Finlay, B.B, Strynadka, N.C.J.
登録日2006-12-19
公開日2007-01-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of a prototypical ATPase from the type III secretion system.
Nat.Struct.Mol.Biol., 14, 2007
2OBM
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Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, EscN
著者Zarivach, R, Vuckovic, M, Deng, W, Finlay, B.B, Strynadka, N.C.J.
登録日2006-12-19
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural analysis of a prototypical ATPase from the type III secretion system.
Nat.Struct.Mol.Biol., 14, 2007
2OBN
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Crystal structure of a duf1611 family protein (ava_3511) from anabaena variabilis atcc 29413 at 2.30 A resolution
分子名称: Hypothetical protein, PHOSPHATE ION, TETRAETHYLENE GLYCOL
著者Joint Center for Structural Genomics (JCSG)
登録日2006-12-19
公開日2007-01-16
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Protein of unknown function DUF1611 (YP_324013.1) from Anabaena variabilis ATCC 29413 at 2.30 A resolution
To be published
2OBO
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Structure of HEPATITIS C VIRAL NS3 protease domain complexed with NS4A peptide and ketoamide SCH476776
分子名称: BETA-MERCAPTOETHANOL, HCV NS3 protease, HCV NS4A peptide, ...
著者Prongay, A.J, Guo, Z, Yao, N, Fischmann, T, Strickland, C, Myers Jr, J, Weber, P.C, Malcolm, B, Beyer, B.M, Ingram, R, Pichardo, J, Hong, Z, Prosise, W.W, Ramanathan, L, Taremi, S.S, Yarosh-Tomaine, T, Zhang, R, Senior, M, Yang, R, Arasappan, A, Bennett, F, Bogen, S.F, Chen, K, Jao, E, Liu, Y, Love, R.G, Saksena, A.K, Venkatraman, S, Girijavallabhan, V, Njoroge, F.G, Madison, V.
登録日2006-12-19
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.
J.Med.Chem., 50, 2007
2OBP
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Crystal structure of a putative dna-binding protein (reut_b4095) from ralstonia eutropha jmp134 at 1.70 A resolution
分子名称: CHLORIDE ION, NITRATE ION, Putative DNA-binding protein
著者Joint Center for Structural Genomics (JCSG)
登録日2006-12-19
公開日2007-01-16
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of putative DNA-binding protein (YP_298295.1) from Ralstonia eutropha JMP134 at 1.70 A resolution
To be published
2OBQ
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Discovery of the HCV NS3/4A Protease Inhibitor SCH503034. Key Steps in Structure-Based Optimization
分子名称: Hepatitis C virus, ZINC ION
著者Prongay, A.J, Guo, Z, Yao, N, Fischmann, T, Strickland, C, Myers Jr, J, Weber, P.C, Malcolm, B, Beyer, B.M, Ingram, R, Pichardo, J, Hong, Z, Prosise, W.W, Ramanathan, L, Taremi, S.S, Yarosh-Tomaine, T, Zhang, R, Senior, M, Yang, R, Arasappan, A, Bennett, F, Bogen, S.F, Chen, K, Jao, E, Liu, Y, Love, R.G, Saksena, A.K, Venkatraman, S, Girijavallabhan, V, Njoroge, F.G, Madison, V.
登録日2006-12-19
公開日2007-07-31
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.
J.Med.Chem., 50, 2007
2OBR
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Crystal Structures of P Domain of Norovirus VA387
分子名称: Capsid protein
著者Cao, S, Lou, Z, Jiang, X, Zhang, X.C, Li, X, Rao, Z.
登録日2006-12-20
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the recognition of blood group trisaccharides by norovirus.
J.Virol., 81, 2007
2OBS
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Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A
分子名称: Capsid protein, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-gulopyranose
著者Cao, S, Li, X, Rao, Z.
登録日2006-12-20
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Recognition of Blood Group Trisaccharides by Norovirus
J.Virol., 81, 2007
2OBT
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Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type B
分子名称: Capsid protein, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose
著者Cao, S, Li, X, Rao, Z.
登録日2006-12-20
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Recognition of Blood Group Trisaccharides by Norovirus
J.Virol., 81, 2007
2OBU
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Solution structure of GIP in TFE/water
分子名称: Gastric inhibitory polypeptide
著者Alana, I, Malthouse, J.P.G, O'Harte, F.P.M, Hewage, C.M.
登録日2006-12-20
公開日2007-06-05
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The bioactive conformation of glucose-dependent insulinotropic polypeptide by NMR and CD spectroscopy
Proteins, 68, 2007
2OBV
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Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product
分子名称: S-ADENOSYLMETHIONINE, S-adenosylmethionine synthetase isoform type-1, SODIUM ION, ...
著者Pilka, E.S, Shafqat, N, Kavanagh, K.L, Cooper, C, Hozjan, V, Turnbull, A, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-12-20
公開日2007-01-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product.
To be Published
2OBX
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Lumazine synthase RibH2 from Mesorhizobium loti (Gene mll7281, Swiss-Prot entry Q986N2) complexed with inhibitor 5-Nitro-6-(D-Ribitylamino)-2,4(1H,3H) Pyrimidinedione
分子名称: 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-dimethyl-8-ribityllumazine synthase 1, PHOSPHATE ION
著者Klinke, S, Zylberman, V, Bonomi, H.R, Haase, I, Guimaraes, B.G, Braden, B.C, Bacher, A, Fischer, M, Goldbaum, F.A.
登録日2006-12-20
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural and kinetic properties of lumazine synthase isoenzymes in the order rhizobiales
J.Mol.Biol., 373, 2007

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