PDB: 10382 件ウェブページステータス検索Chemie searchBIRD

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7QJ6	Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, substoichiometric spokes 13-14) 分子名称: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... 著者 Zupa, E, Pfeffer, S. 登録日 2021-12-16 公開日 2022-01-26 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Modular assembly of the principal microtubule nucleator gamma-TuRC. Nat Commun, 13, 2022
5MJ4	INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 2 分子名称: ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ... 著者 Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Henderikx, P, Lasters, I, Savvides, S. 登録日 2016-11-29 公開日 2017-01-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 STRUCTURAL BASIS OF IL-23 ANTAGONISM BY AN ALPHABODY PROTEIN Nature Communications, 5, 2014
4MDF	Structure of bacterial polynucleotide kinase Michaelis complex bound to GTP and DNA 分子名称: CITRIC ACID, DNA (5'-D(*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. 登録日 2013-08-22 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.727 Å) 主引用文献 Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
5MJ3	INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 1 分子名称: ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ... 著者 Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Hendrikx, P, Lasters, I, Savvides, S.N. 登録日 2016-11-29 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural Basis Of Il-23 Antagonism By An Alphabody Protein Scaffold. Nat Commun, 5, 2014
4MD7	Crystal Structure of full-length symmetric CK2 holoenzyme 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
3AAD	Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction 分子名称: Histone chaperone ASF1A, SULFATE ION, Transcription initiation factor TFIID subunit 1 著者 Akai, Y, Adachi, N, Hayashi, Y, Eitoku, M, Sano, N, Natsume, R, Kudo, N, Tanokura, M, Senda, T, Horikoshi, M. 登録日 2009-11-16 公開日 2010-04-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction Proc.Natl.Acad.Sci.USA, 107, 2010
1QAI	CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN 分子名称: DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3'), MERCURY (II) ION, REVERSE TRANSCRIPTASE 著者 Najmudin, S, Cote, M, Sun, D, Yohannan, S, Montano, S.P, Gu, J, Georgiadis, M.M. 登録日 1999-03-12 公開日 2000-03-20 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain. J.Mol.Biol., 296, 2000
8BBG	Structure of the IFT-A complex; anterograde IFT-A train model 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... 著者 Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. 登録日 2022-10-12 公開日 2022-12-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 IFT-A structure reveals carriages for membrane protein transport into cilia. Cell, 185, 2022
8BBE	Structure of the IFT-A complex; IFT-A2 module 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, SNAP-tag,Tetratricopeptide repeat protein 21B, ... 著者 Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. 登録日 2022-10-12 公開日 2022-12-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 IFT-A structure reveals carriages for membrane protein transport into cilia. Cell, 185, 2022
4MD9	Crystal Structure of symmetric CK2 holoenzyme with mutated alpha subunit (F121E truncated at aa 336) 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
4MVA	1.43 Angstrom Resolution Crystal Structure of Triosephosphate Isomerase (tpiA) from Escherichia coli in Complex with Acetyl Phosphate. 分子名称: 1,2-ETHANEDIOL, ACETYLPHOSPHATE, CHLORIDE ION, ... 著者 Minasov, G, Kuhn, M.L, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-09-23 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. Plos One, 9, 2014
4MDE	Structure of bacterial polynucleotide kinase product complex bound to GDP and DNA 分子名称: DNA (5'-D(P*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. 登録日 2013-08-22 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
4MD8	Crystal Structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E) 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
5ZMC	Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 分子名称: DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ... 著者 Xu, X, Bharath, S.R, Song, H. 登録日 2018-04-02 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1. Nat Commun, 9, 2018
5CYI	CDK2/Cyclin A covalent complex with 6-(cyclohexylmethoxy)-N-(4-(vinylsulfonyl)phenyl)-9H-purin-2-amine (NU6300) 分子名称: 6-(cyclohexylmethoxy)-N-[4-(ethylsulfonyl)phenyl]-9H-purin-2-amine, Cyclin-A2, Cyclin-dependent kinase 2 著者 Anscombe, E, Meschini, E, Vidal, R.M, Martin, M.P, Staunton, D, Geitmann, M, Danielson, U.H, Stanley, W.A, Wang, L.Z, Reuillon, T, Golding, B.T, Cano, C, Newell, D.R, Noble, M.E.M, Wedge, S.R, Endicott, J.A, Griffin, R.J. 登録日 2015-07-30 公開日 2015-09-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem.Biol., 22, 2015
4OGR	crystal structure of P-TEFb complex with AFF4 and Tat 分子名称: ADENOSINE, AF4/FMR2 family member 4, Cyclin-T1, ... 著者 Schulze-Gahmen, U, Alber, T. 登録日 2014-01-16 公開日 2014-05-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter. Elife, 3, 2014
2MEV	STRUCTURAL REFINEMENT AND ANALYSIS OF MENGO VIRUS 分子名称: MENGO VIRUS COAT PROTEIN (SUBUNIT VP1), MENGO VIRUS COAT PROTEIN (SUBUNIT VP2), MENGO VIRUS COAT PROTEIN (SUBUNIT VP3), ... 著者 Rossmann, M.G. 登録日 1989-04-21 公開日 1990-01-15 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural refinement and analysis of Mengo virus. J.Mol.Biol., 211, 1990
2MPL	Solution structure of the PR domain of FOG-1 分子名称: Zinc finger protein ZFPM1 著者 Mackay, J.P, Clifton, M.K, Westman, B.J, Blobel, G.A. 登録日 2014-05-26 公開日 2014-10-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins. Plos One, 9, 2014
1FMO	CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE 分子名称: ADENOSINE, CAMP-DEPENDENT PROTEIN KINASE, HEAT STABLE RABBIT SKELETAL MUSCLE INHIBITOR PROTEIN 著者 Narayana, N, Cox, S, Shaltiel, S, Taylor, S.S, Xuong, N.-H. 登録日 1997-07-08 公開日 1998-01-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine. Biochemistry, 36, 1997
3FJB	Crystal structure of V31I mutant of Human acidic fibroblast growth factor 分子名称: Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2008-12-14 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009
3O7L	Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex 分子名称: Cardiac phospholamban, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Cheng, C.Y, Taylor, S.S. 登録日 2010-07-30 公開日 2010-10-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dynamics connect substrate recognition to catalysis in protein kinase A. Nat.Chem.Biol., 6, 2010
3FJA	Crystal structure of F132W mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1 著者 Blaber, M, Lee, J. 登録日 2008-12-14 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009
2QVU	Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Mg2+, I(T)-state 分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ... 著者 Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B. 登録日 2007-08-08 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition J.Biol.Chem., 282, 2007
1INR	CYTOKINE SYNTHESIS 分子名称: INTERLEUKIN-10 著者 Walter, M.R. 登録日 1995-07-31 公開日 1996-10-14 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of interleukin 10 reveals an interferon gamma-like fold. Biochemistry, 34, 1995
4DGL	Crystal Structure of the CK2 Tetrameric Holoenzyme 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Battistutta, R. 登録日 2012-01-26 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization. Acs Chem.Biol., 7, 2012

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