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3PZP
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BU of 3pzp by Molmil
Human DNA polymerase kappa extending opposite a cis-syn thymine dimer
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3', 5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ...
著者Vasquez-Del Carpio, R, Silverstein, T.D, Lone, S, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K.
登録日2010-12-14
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.336 Å)
主引用文献Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer.
J.Mol.Biol., 408, 2011
4EEY
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BU of 4eey by Molmil
Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*GP*GP*TP*CP*TP*CP*CP*TP*CP*C)-3', 5'-D(*TP*GP*GP*AP*GP*GP*AP*GP*A)-3', ...
著者Ummat, A, Rechkoblit, O, Jain, R, Choudhury, J.R, Johnson, R.E, Silverstein, T.D, Buku, A, Lone, S, Prakash, L, Prakash, S, Aggarwal, A.K.
登録日2012-03-28
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural basis for cisplatin DNA damage tolerance by human polymerase {eta} during cancer chemotherapy.
Nat.Struct.Mol.Biol., 19, 2012
3Q8P
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BU of 3q8p by Molmil
Human DNA polymerase iota incorporating dCTP opposite 8-oxo-guanine
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ...
著者Kirouac, K.N, Ling, H.
登録日2011-01-06
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q8Q
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BU of 3q8q by Molmil
Human DNA polymerase iota incorporating dATP opposite 8-oxo-guanine
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ...
著者Kirouac, K.N, Ling, H.
登録日2011-01-06
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.031 Å)
主引用文献Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.
Proc.Natl.Acad.Sci.USA, 108, 2011
6I1L
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BU of 6i1l by Molmil
Crystal structure of FnCas12a in complex with a crRNA guide and ssDNA target
分子名称: CITRIC ACID, CRISPR-associated endonuclease Cas12a, MAGNESIUM ION, ...
著者Jinek, M, Swarts, D.C.
登録日2018-10-29
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell, 73, 2019
3IFZ
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BU of 3ifz by Molmil
crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit A, SODIUM ION
著者Piton, J, Aubry, A, Delarue, M, Mayer, C.
登録日2009-07-27
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.
Plos One, 5, 2010
3Q8R
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BU of 3q8r by Molmil
Human DNA polymerase iota incorporating dGTP opposite 8-oxo-guanine
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ...
著者Kirouac, K.N, Ling, H.
登録日2011-01-06
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.
Proc.Natl.Acad.Sci.USA, 108, 2011
3WAZ
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BU of 3waz by Molmil
Crystal structure of a restriction enzyme PabI in complex with DNA
分子名称: ADENINE, DNA (5'-D(*GP*CP*AP*TP*AP*GP*CP*TP*GP*TP*(ORP)P*CP*AP*GP*CP*TP*AP*TP*GP*C)-3'), Putative uncharacterized protein
著者Miyazono, K, Miyakawa, T, Ito, T, Tanokura, M.
登録日2013-05-10
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A sequence-specific DNA glycosylase mediates restriction-modification in Pyrococcus abyssi.
Nat Commun, 5, 2014
8QAM
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BU of 8qam by Molmil
vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K
分子名称: GLYCEROL, SULFATE ION, Uracil-DNA glycosylase
著者Tarbouriech, N, Burmeister, W.P.
登録日2023-08-23
公開日2024-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus.
Plos Pathog., 20, 2024
5CDM
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BU of 5cdm by Molmil
2.5A structure of QPT-1 with S.aureus DNA gyrase and DNA
分子名称: (2R,4S,4aS)-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1'H,3'H)-trione, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
3OSP
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BU of 3osp by Molmil
Structure of rev1
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ...
著者Nair, D.T, Aggarwal, A.K.
登録日2010-09-09
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase.
J.Mol.Biol., 406, 2011
1MWI
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BU of 1mwi by Molmil
Crystal structure of a MUG-DNA product complex
分子名称: 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase
著者Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H.
登録日2002-09-30
公開日2002-10-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
7LMK
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BU of 7lmk by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3
分子名称: DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
著者Ren, W, Song, J.
登録日2021-02-05
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.647 Å)
主引用文献DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
4B21
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BU of 4b21 by Molmil
Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2
分子名称: 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', PHOSPHATE ION, ...
著者Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M.
登録日2012-07-12
公開日2013-01-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
Structure, 21, 2013
8BP2
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BU of 8bp2 by Molmil
2.8A STRUCTURE OF ZOLIFLODACIN WITH S.AUREUS DNA GYRASE AND DNA
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (20-MER), DNA gyrase subunit A, ...
著者Bax, B.D, Morgan, H, Warren, A.J.
登録日2022-11-15
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A 2.8 angstrom Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase.
Int J Mol Sci, 24, 2023
6TYW
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BU of 6tyw by Molmil
Structure of Ku80 von Willebrand domain S229A mutant complexed with APLF Ku Binding Motif
分子名称: 1,2-ETHANEDIOL, GLU-ARG-LYS-ARG-ILE-LEU-PRO-THR-TRP-MET-LEU-ALA-GLU, X-ray repair cross-complementing protein 5
著者Min, J, Pedersen, L.C.
登録日2019-08-09
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.69965541 Å)
主引用文献Ligand binding characteristics of the Ku80 von Willebrand domain.
DNA Repair (Amst.), 85, 2019
6TYZ
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BU of 6tyz by Molmil
Structure of Ku80 von Willebrand domain complexed with APLF Ku Binding Motif
分子名称: 1,2-ETHANEDIOL, GLU-ARG-LYS-ARG-ILE-LEU-PRO-THR-TRP-MET-LEU-ALA, X-ray repair cross-complementing protein 5
著者Min, J, Pedersen, L.C.
登録日2019-08-09
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.51076627 Å)
主引用文献Ligand binding characteristics of the Ku80 von Willebrand domain.
DNA Repair (Amst.), 85, 2019
6TYV
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BU of 6tyv by Molmil
Structure of Ku80 von Willebrand domain complexed with WRN Ku Binding Motif
分子名称: THR-THR-ALA-GLN-GLN-ARG-LYS-CYS-PRO-GLU-TRP-MET-ASN, X-ray repair cross-complementing protein 5
著者Min, J, Pedersen, L.C.
登録日2019-08-09
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.926111 Å)
主引用文献Ligand binding characteristics of the Ku80 von Willebrand domain.
DNA Repair (Amst.), 85, 2019
6TYX
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BU of 6tyx by Molmil
Structure of Ku80 von Willebrand domain S229A mutant complexed with XLF Ku Binding Motif
分子名称: LYS-GLY-LEU-PHE-MET, X-ray repair cross-complementing protein 5
著者Min, J, Pedersen, L.C.
登録日2019-08-09
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.89944351 Å)
主引用文献Ligand binding characteristics of the Ku80 von Willebrand domain.
DNA Repair (Amst.), 85, 2019
7W5P
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BU of 7w5p by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA
分子名称: CcTet, DNA, DNA (12-MER), ...
著者Mu, Y.J, Zhang, L, Zhang, L.
登録日2021-11-30
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA.
Nat.Chem.Biol., 18, 2022
7YHS
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BU of 7yhs by Molmil
Structure of Csy-AcrIF4-dsDNA
分子名称: AcrIF4, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Feng, Y, Zhang, L.X.
登録日2022-07-14
公開日2023-03-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage.
J.Biol.Chem., 298, 2022
6TYU
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BU of 6tyu by Molmil
Structure of Ku80 von Willebrand domain complexed with MRI Ku Binding Motif
分子名称: LYS-THR-ARG-VAL-LEU-PRO-SER-TRP-LEU-THR-ALA, X-ray repair cross-complementing protein 5
著者Min, J, Pedersen, L.C.
登録日2019-08-09
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.46862721 Å)
主引用文献Ligand binding characteristics of the Ku80 von Willebrand domain.
DNA Repair (Amst.), 85, 2019
4B24
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BU of 4b24 by Molmil
Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2
分子名称: 5'-D(*CP*GP*AP*TP*AP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*TP*AP*TP*CP*GP)-3', PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE 2
著者Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M.
登録日2012-07-12
公開日2013-01-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
Structure, 21, 2013
7VW3
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BU of 7vw3 by Molmil
Cryo-EM structure of SaCas9-sgRNA-DNA ternary complex
分子名称: CRISPR-associated endonuclease Cas9, MAGNESIUM ION, Non-target DNA strand, ...
著者Du, W.H, Qian, J.Q, Huang, Q.
登録日2021-11-09
公開日2023-03-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State.
Int J Mol Sci, 24, 2023
6TYT
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BU of 6tyt by Molmil
Structure of Ku80 von Willebrand domain S229A mutant complexed with APLF and XLF Ku Binding Motif
分子名称: ALA-LYS-GLY-LEU-PHE-MET, ARG-LYS-ARG-ILE-LEU-PRO-THR-TRP-MET-LEU-ALA, X-ray repair cross-complementing protein 5
著者Min, J, Pedersen, L.C.
登録日2019-08-09
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.403488 Å)
主引用文献Ligand binding characteristics of the Ku80 von Willebrand domain.
DNA Repair (Amst.), 85, 2019

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