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2NNC
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Structure of the sulfur carrier protein SoxY from Chlorobium limicola f thiosulfatophilum
分子名称: CHLORIDE ION, NITROGEN MOLECULE, PHOSPHATE ION, ...
著者Stout, J, Van Driessche, G, Savvides, S.N, Van Beeumen, J.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure.
Protein Sci., 16, 2007
2NND
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The Structural Identification of the Interaction Site and Functional State of RBP for its Membrane Receptor
分子名称: 2-ISOBUTYL-3-METHOXYPYRAZINE, CADMIUM ION, Major urinary protein 2
著者Redondo, C, Bingham, R.J, Vouropoulou, M, Homans, S.W, Findlay, J.B.
登録日2006-10-24
公開日2007-10-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of the retinol-binding protein (RBP) interaction site and functional state of RBPs for the membrane receptor.
Faseb J., 22, 2008
2NNE
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The Structural Identification of the Interaction Site and Functional State of RBP for its Membrane Receptor
分子名称: CADMIUM ION, GLYCEROL, Major urinary protein 2
著者Redondo, C, Bingham, R.J, Vouropoulou, M, Homans, S.W, Findlay, J.B.
登録日2006-10-24
公開日2007-10-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of the retinol-binding protein (RBP) interaction site and functional state of RBPs for the membrane receptor.
Faseb J., 22, 2008
2NNF
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Structure of the sulfur carrier protein SoxY from Chlorobium limicola f thiosulfatophilum
分子名称: PHOSPHATE ION, Sulfur covalently-binding protein
著者Stout, J, Van Driessche, G, Savvides, S.N, Van Beeumen, J.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure.
Protein Sci., 16, 2007
2NNG
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Structure of inhibitor binding to Carbonic Anhydrase II
分子名称: 4-(2-AMINOETHYL)BENZENESULFONAMIDE, Carbonic anhydrase 2, GLYCEROL, ...
著者Christianson, D.W, Jude, K.M.
登録日2006-10-24
公開日2007-05-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNH
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CYP2C8dH complexed with 2 molecules of 9-cis retinoic acid
分子名称: (9cis)-retinoic acid, Cytochrome P450 2C8, PALMITIC ACID, ...
著者Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F.
登録日2006-10-24
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
J.Biol.Chem., 283, 2008
2NNI
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CYP2C8dH complexed with montelukast
分子名称: Cytochrome P450 2C8, MONTELUKAST, PALMITIC ACID, ...
著者Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F.
登録日2006-10-24
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
J.Biol.Chem., 283, 2008
2NNJ
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CYP2C8dH complexed with felodipine
分子名称: Cytochrome P450 2C8, FELODIPINE, PALMITIC ACID, ...
著者Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F.
登録日2006-10-24
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
J.Biol.Chem., 283, 2008
2NNK
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Crystal structure analysis of HIV-1 protease mutant I84V with a inhibitor saquinavir
分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETIC ACID, CHLORIDE ION, ...
著者Tie, Y, Kovalevsky, A.Y, Boross, P, Wang, Y.F, Ghosh, A.K, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir.
Proteins, 67, 2007
2NNL
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Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site
分子名称: (2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, Dihydroflavonol 4-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Petit, P, Langlois D'Estaintot, B, Granier, T, Gallois, B.
登録日2006-10-24
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site
To be Published
2NNN
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Crystal structure of probable transcriptional regulator from Pseudomonas aeruginosa
分子名称: Probable transcriptional regulator
著者Chang, C, Evdokimova, E, Altamentova, S, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-10-24
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of probable transcriptional regulator from Pseudomonas aeruginosa
To be Published
2NNO
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Structure of inhibitor binding to Carbonic Anhydrase II
分子名称: 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID, Carbonic anhydrase 2, GLYCEROL, ...
著者Christianson, D.W, Jude, K.M.
登録日2006-10-24
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.01 Å)
主引用文献Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNP
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Crystal structure analysis of HIV-1 protease mutant I84V with a inhibitor saquinavir
分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETIC ACID, GLYCEROL, ...
著者Tie, Y, Kovalevsky, A.Y, Boross, P, Wang, Y.F, Ghosh, A.K, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir.
Proteins, 67, 2007
2NNQ
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Crystal structure of human adipocyte fatty acid binding protein in complex with ((2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-3-biphenylyl)oxy)acetic acid
分子名称: ((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPHENYLYL)OXY)ACETIC ACID, Fatty acid-binding protein, adipocyte, ...
著者Jacobson, B.L.
登録日2006-10-24
公開日2007-06-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).
Bioorg.Med.Chem.Lett., 17, 2007
2NNR
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Crystal structure of chagasin, cysteine protease inhibitor from Trypanosoma cruzi
分子名称: CHLORIDE ION, Chagasin, GLYCEROL, ...
著者Redzynia, I, Bujacz, G, Ljunggren, A, Jaskolski, M, Abrahamson, M.
登録日2006-10-24
公開日2007-07-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
J.Mol.Biol., 371, 2007
2NNS
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Structure of inhibitor binding to Carbonic Anhydrase II
分子名称: CHLORIDE ION, Carbonic anhydrase 2, GLYCEROL, ...
著者Christianson, D.W, Jude, K.M.
登録日2006-10-24
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNT
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General structural motifs of amyloid protofilaments
分子名称: Transcription elongation regulator 1
著者Ferguson, N, Becker, J, Tidow, H, Tremmel, S, Sharpe, T.D, Krause, G, Flinders, J, Petrovich, M, Berriman, J, Oschkinat, H, Fersht, A.R.
登録日2006-10-24
公開日2006-11-14
最終更新日2023-12-27
実験手法SOLID-STATE NMR
主引用文献General structural motifs of amyloid protofilaments.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2NNU
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Crystal Structure of the Papillomavirus DNA Tethering Complex E2:Brd4
分子名称: Bromodomain-containing protein 4, Regulatory protein E2
著者Abbate, E.A, Voitenleitner, C, Botchan, M.R.
登録日2006-10-24
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure of the Papillomavirus DNA-Tethering Complex E2:Brd4 and a Peptide that Ablates HPV Chromosomal Association.
Mol.Cell, 24, 2006
2NNV
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Structure of inhibitor binding to Carbonic Anhydrase II
分子名称: Carbonic anhydrase 2, ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE, GLYCEROL, ...
著者Christianson, D.W, Jude, K.M.
登録日2006-10-24
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNW
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Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs
分子名称: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein
著者Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H.
登録日2006-10-24
公開日2007-08-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.
J.Mol.Biol., 371, 2007
2NNX
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Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase
分子名称: SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Schuermann, J.P, Hart, P.J.
登録日2006-10-24
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability
J.Biol.Chem., 282, 2007
2NNY
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Crystal structure of the Ets1 dimer DNA complex.
分子名称: 5'-D(*A*CP*TP*CP*CP*AP*GP*GP*AP*AP*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*TP*CP*T)-3', 5'-D(*T*AP*GP*AP*CP*AP*GP*GP*AP*AP*GP*CP*AP*CP*TP*TP*CP*CP*TP*GP*GP*AP*G)-3', C-ets-1 protein
著者Lamber, E.P, Kachalova, G.S, Wilmanns, M.
登録日2006-10-24
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization.
Embo J., 27, 2008
2NNZ
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Solution structure of the hypothetical protein AF2241 from Archaeoglobus fulgidus
分子名称: Hypothetical protein
著者Ai, X, Semesib, A, Yee, A, Arrowsmith, C.H, Li, S.S.C, Choy, W.Y, Ontario Centre for Structural Proteomics (OCSP)
登録日2006-10-24
公開日2007-08-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Hypothetical protein AF2241 from Archaeoglobus fulgidus adopts a cyclophilin-like fold.
J.Biomol.Nmr, 38, 2007
2NO0
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C4S dCK variant of dCK in complex with gemcitabine+ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, GEMCITABINE
著者Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A.
登録日2006-10-24
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
2NO1
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C4S dCK variant of dCK in complex with D-dC+ADP
分子名称: 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
著者Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A.
登録日2006-10-24
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007

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