PDB: 55616 件ウェブページステータス検索Chemie searchBIRD

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4BQD	KD1 of human TFPI in complex with a synthetic peptide 分子名称: GLYCEROL, PEPTIDE, TISSUE FACTOR PATHWAY INHIBITOR (LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR) VARIANT 著者 Griessner, A, Brandstetter, H. 登録日 2013-05-30 公開日 2013-12-04 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor Viia by Tissue Factor Pathway Inhibitor (Tfpi) J.Biol.Chem., 289, 2014
3N0P	A mutant human Prolactin receptor antagonist H30A in complex with the extracellular domain of the human prolactin receptor 分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ... 著者 Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. 登録日 2010-05-14 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
5OIM	InhA (T2A mutant) complexed with ethyl 2-methyl-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate 分子名称: 2-ETHOXYETHANOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Convery, M.A. 登録日 2017-07-19 公開日 2018-02-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA. ChemMedChem, 13, 2018
3S3W	Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive cation channel 2, ... 著者 Dawson, R.J.P, Benz, J, Stohler, P, Tetaz, T, Joseph, C, Huber, S, Schmid, G, Huegin, D, Pflimlin, P, Trube, G, Rudolph, M.G, Hennig, M, Ruf, A. 登録日 2011-05-18 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1. Nat Commun, 3, 2012
2E59	Crystal structure of human MD-2 in complex with lipid IVa 分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, ... 著者 Ohto, U, Satow, Y. 登録日 2006-12-19 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa Science, 316, 2007
4CMH	Crystal structure of CD38 with a novel CD38-targeting antibody SAR650984 分子名称: ADP-RIBOSYL CYCLASE 1, HEAVY CHAIN OF SAR650984-FAB FRAGMENT, LIGHT CHAIN OF SAR650984-FAB FRAGMENT 著者 Deckert, J, Wetzel, M.C, Park, P.U, Bartle, L.M, Skaletskaya, A, Goldmacher, V, Vallee, F, ZhouLiu, Q, Ferrari, P, Pouzieux, S, Lahoute, C, Dumontet, C, Plesa, A, Chiron, M, Lejeune, P, Chittenden, T, Blanc, V. 登録日 2014-01-15 公開日 2014-07-16 最終更新日 2018-10-24 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies. Clin. Cancer Res., 20, 2014
6R28	Structure of peptide P7, which binds Cdc42 and inhibits effector interactions. 分子名称: peptide P7 著者 Murphy, N.P, Mott, H.R, Owen, D. 登録日 2019-03-15 公開日 2020-01-29 最終更新日 2024-03-06 実験手法 SOLUTION NMR 主引用文献 The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling. J.Biol.Chem., 295, 2020
3NCE	A mutant human Prolactin receptor antagonist H27A in complex with the mutant extracellular domain H188A of the human prolactin receptor 分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ... 著者 Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. 登録日 2010-06-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
2HK4	Dimeric solution structure of the cyclic octamer d(CCGTCCGT) 分子名称: 5'-D(P*CP*CP*GP*TP*CP*CP*GP*T)-3' 著者 Escaja, N, Gomez-Pinto, I, Pedroso, E, Gonzalez, C. 登録日 2006-07-03 公開日 2007-03-20 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Four-stranded DNA structures can be stabilized by two different types of minor groove G:C:G:C tetrads. J.Am.Chem.Soc., 129, 2007
1CQN	PROTEIN AGGREGATION AND ALZHEIMER'S DISEASE: CRYSTALLOGRAPHIC ANALYSIS OF THE PHENOMENON. ENGINEERED VERSION OF THE RIBOSOMAL PROTEIN S6 USED AS A STABLE SCAFFOLD TO STUDY OLIGOMERIZATION. 分子名称: RIBOSOMAL PROTEIN S6 著者 Kristensen, O, Otzen, D.E, Oliveberg, M. 登録日 1999-08-08 公開日 2000-09-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly. Proc.Natl.Acad.Sci.USA, 97, 2000
1D83	STRUCTURE REFINEMENT OF THE CHROMOMYCIN DIMER/DNA OLIGOMER COMPLEX IN SOLUTION 分子名称: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... 著者 Gao, X, Mirau, P, Patel, D.J. 登録日 1992-07-22 公開日 1993-07-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure refinement of the chromomycin dimer-DNA oligomer complex in solution. J.Mol.Biol., 223, 1992
1CQM	PROTEIN AGGREGATION AND ALZHEIMER'S DISEASE: CRYSTALLOGRAPHIC ANALYSIS OF THE PHENOMENON. ENGINEERED VERSION OF THE RIBOSOMAL PROTEIN S6 USED AS A STABLE SCAFFOLD TO STUDY OLIGOMERIZATION. 分子名称: RIBOSOMAL PROTEIN S6 著者 Kristensen, O, Otzen, D.E, Oliveberg, M. 登録日 1999-08-08 公開日 2000-09-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly. Proc.Natl.Acad.Sci.USA, 97, 2000
3NCC	A human Prolactin receptor antagonist in complex with the mutant extracellular domain H188A of the human prolactin receptor 分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ... 著者 Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. 登録日 2010-06-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
2OPT	Crystal Structure of Apo ActR from Streptomyces coelicolor. 分子名称: ActII protein 著者 Willems, A.R, Junop, M.S. 登録日 2007-01-30 公開日 2008-02-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA. J.Mol.Biol., 376, 2008
4BK6	Crystal Structure of a dimeric variant of Bet v 1 分子名称: MAJOR POLLEN ALLERGEN BET V 1-A 著者 Kofler, S.G, Brandstetter, H. 登録日 2013-04-22 公開日 2013-11-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Stabilization of the Dimeric Birch Pollen Allergen Bet V 1 Impacts its Immunological Properties J.Biol.Chem., 289, 2014
2OM9	Ajulemic acid, a synthetic cannabinoid bound to PPAR gamma 分子名称: (6AR,10AR)-3-(1,1-DIMETHYLHEPTYL)-1-HYDROXY-6,6-DIMETHYL-6A,7,10,10A-TETRAHYDRO-6H-BENZO[C]CHROMENE-9-CARBOXYLIC ACID, Peroxisome proliferator-activated receptor gamma 著者 Ambrosio, A.L.B, Garratt, R.C. 登録日 2007-01-21 公開日 2007-04-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ajulemic Acid, a Synthetic Nonpsychoactive Cannabinoid Acid, Bound to the Ligand Binding Domain of the Human Peroxisome Proliferator-activated Receptor gamma J.Biol.Chem., 282, 2007
3NCB	A mutant human Prolactin receptor antagonist H180A in complex with the extracellular domain of the human prolactin receptor 分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ... 著者 Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. 登録日 2010-06-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
3NCF	A mutant human Prolactin receptor antagonist H30A in complex with the mutant extracellular domain H188A of the human prolactin receptor 分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ... 著者 Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. 登録日 2010-06-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
4BTZ	Crystal Structure of peroxinitrite treated Major Birch Pollen Allergen Bet v 1.0101 (isoform a) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A 著者 Kofler, S.G, Ackaert, C, Brandstetter, H. 登録日 2013-06-19 公開日 2014-07-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 The Crystal Structure of the Major Birch Pollen Allergen Bet V 1 After Nitration with Peroxinitrite To be Published
2OBF	Structure of K57A hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy (SAH) 分子名称: (3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2006-12-19 公開日 2007-10-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase J.Med.Chem., 50, 2007
4BPW	Crystal structure of human primase bound to UTP 分子名称: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ... 著者 Kilkenny, M.L, Perera, R.L, Pellegrini, L. 登録日 2013-05-28 公開日 2013-09-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.003 Å) 主引用文献 Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering Proc.Natl.Acad.Sci.USA, 110, 2013
7UN8	SfSTING with c-di-GMP single fiber 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12 著者 Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. 登録日 2022-04-09 公開日 2022-07-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
7UN9	SfSTING with c-di-GMP double fiber 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12 著者 Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. 登録日 2022-04-09 公開日 2022-07-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
7UNA	SfSTING with cGAMP (masked) 分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CD-NTase-associated protein 12 著者 Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. 登録日 2022-04-09 公開日 2022-07-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
2ONY	Structure of hPNMT with inhibitor 7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy 分子名称: N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, PHOSPHATE ION, Phenylethanolamine N-methyltransferase, ... 著者 Drinkwater, N, Martin, J.L. 登録日 2007-01-24 公開日 2007-10-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase J.Med.Chem., 50, 2007

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