8RBO
| Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation | 分子名称: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | 著者 | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | 登録日 | 2023-12-04 | 公開日 | 2024-04-24 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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8RCL
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8QZZ
| Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452 | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Yan, Y, Ron, D. | 登録日 | 2023-10-30 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Substrate recruitment via eIF2 gamma enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proc.Natl.Acad.Sci.USA, 121, 2024
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8S5N
| RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-24 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S55
| RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S51
| RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S52
| RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S54
| RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8UHD
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8UI0
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8UHG
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8UHA
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8UIS
| Structure of transcription complex Pol II-DSIF-NELF-TFIIS | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | 著者 | Su, B.G, Vos, S.M. | 登録日 | 2023-10-10 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
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8TVP
| Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVV
| Cryo-EM structure of backtracked Pol II | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVX
| Cryo-EM structure of CPD-stalled Pol II (Conformation 2) | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVY
| Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVW
| Cryo-EM structure of CPD-stalled Pol II (conformation 1) | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVS
| Cryo-EM structure of backtracked Pol II in complex with Rad26 | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TUG
| Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-16 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8WAS
| Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-08 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (6.13 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAV
| De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt downstream of TSS | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-08 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAP
| Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-08 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (5.85 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAN
| Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (6.07 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAL
| Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (8.52 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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